Postoperative Analgesia in Patients With Microvascular Decompression
NCT ID: NCT03152955
Last Updated: 2018-05-15
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
PHASE4
90 participants
INTERVENTIONAL
2017-05-15
2018-05-15
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
QUADRUPLE
Study Groups
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Group A
Patients in Group A will receive scalp nerve block and patient-controlled analgesia which contains sufentanil and ondansetron.
scalp nerve block
Scalp nerve block is performed for the blockade of the greater occipital, superficial cervical and lesser occipital nerves with 0.5% ropivacaine.
ondansetron
Ondansetron(13ug/kg/h) is applied in patient-controlled analgesia.
Sufentanil
Sufentanil(0.02ug/kg/h) is applied in patient-controlled analgesia.
Group B
In Group B, patient-controlled analgesia which contains sufentanil、ondansetron and ketamine will be applied.
Ketamine
Ketamine will be applied in patient-controlled analgesia.
ondansetron
Ondansetron(13ug/kg/h) is applied in patient-controlled analgesia.
Sufentanil
Sufentanil(0.02ug/kg/h) is applied in patient-controlled analgesia.
Group C
In Group C, patient-controlled analgesia which contains sufentanil and ondansetron will be applied.
ondansetron
Ondansetron(13ug/kg/h) is applied in patient-controlled analgesia.
Sufentanil
Sufentanil(0.02ug/kg/h) is applied in patient-controlled analgesia.
Interventions
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Ketamine
Ketamine will be applied in patient-controlled analgesia.
scalp nerve block
Scalp nerve block is performed for the blockade of the greater occipital, superficial cervical and lesser occipital nerves with 0.5% ropivacaine.
ondansetron
Ondansetron(13ug/kg/h) is applied in patient-controlled analgesia.
Sufentanil
Sufentanil(0.02ug/kg/h) is applied in patient-controlled analgesia.
Eligibility Criteria
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Inclusion Criteria
2. Age between 18 and 70, ASA classification between Ⅰ～Ⅲ
3. No severe liver and kidney disease, no blood coagulation dysfunction
4. No history of long-term opioid drugs usage, no drug addiction history
5. Patients are fully conscious, cooperation, understanding and voluntarily signed informed consent
Exclusion Criteria
2. Intracranial hematoma happens within 24 h after surgery
3. Secondary surgery patients
18 Years
70 Years
ALL
Yes
Sponsors
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Xiangya Hospital of Central South University
OTHER
Responsible Party
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Principal Investigators
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Xie Yongqiu
Role: STUDY_DIRECTOR
Xiangya Hospital of Central South University in Changsha
Locations
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Xiangya Hospital of Central South University
Changsha, Hunan, China
Countries
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Other Identifiers
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XiangyaHospital
Identifier Type: -
Identifier Source: org_study_id
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