Altered MAstication Contribute to TMJ PAin

NCT ID: NCT03139994

Last Updated: 2021-10-01

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 30 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2017-05-02
• Study Completion Date: 2018-10-30

Brief Summary

The cause of temporomandibular joint disorders remains unknown. It is considered multifactorial and includes physical (peripheral) and psychosocial (central) factors. It has been showed an association: a steeper condylar path, flatter lateral anterior guidance, and habitual chewing on the symptomatic side. This finding argues the possibility of causation of some of these characteristics. This double blind longitudinal study aims to assess if the presence of one habitual chewing side could contribute to temporomandibular joint disorders over time.

Method. Young adults with no signs or symptoms of TMD will be assessed. Participants with one chewing side (observed and interview); with steeper condylar path and lower lateral guidance angles will be considered consistent one side chewers, and this side will be considered more susceptible to suffer TMD. Mouth opening, hemispheric dominance and hemimandibular retrognathia will be considered as secondary pre-specified outcomes. Four years later, both TMJs of each participant presenting signs and/or symptoms will be evaluated according to DC/TMD.

Conditions

Temporomandibular Joint Disorders; Mastication Disorder

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Interventions

Diagnostic

OBSERVATIONAL, DIAGNOSTIC PROCEDURES. Young adults with no signs or symptoms of TMD will be assessed. The chewing function, condylar path angles and lateral guidance angles will be recorded. Maximum comfortable and unassisted jaw opening, hemispheric dominance and hemimandibular retrognathia will be considered as secondary pre-specified outcomes. Three-Four years later, both TMJs of each participant presenting signs and/or symptoms will be evaluated according to DC/TMD. Same recordings as baseline will be carried out.

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• healthies
• full dentates
• normal occlusion
• One habitual chewing side

Exclusion Criteria

• Severe malocclusion, dental decay, severe periodontal disease.

Pains from other origins or Orthodontics are not criteria for exclusion

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 30 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

University of Santiago de Compostela

OTHER

Sponsor Role: lead

Responsible Party

Urbano Santana Penin, MD, DDS, PhD

PROFESSOR

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Urbano Santana-Mora, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Santiago de Compostela. Spain

Urbano Santana, Prof.

Role: STUDY_CHAIR

University of Santiago de Compostela. Spain

Mª Jesús Mora

Role: PRINCIPAL_INVESTIGATOR

University of Santiago de Compostela. Spain

Locations

University of Santiago de Compostela

Santiago de Compostela, A Coruña, Spain

Countries

Spain

References

Santana-Mora U, Lopez-Cedrun J, Mora MJ, Otero XL, Santana-Penin U. Temporomandibular disorders: the habitual chewing side syndrome. PLoS One. 2013 Apr 8;8(4):e59980. doi: 10.1371/journal.pone.0059980. Print 2013.

Reference Type: RESULT

PMID: 23593156 (View on PubMed)

Other Identifiers

20130123

Identifier Type: -

Identifier Source: org_study_id