Interest of MRI in Preoperative Staging for the Laryngeal and Hypopharyngeal Cancer

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

73 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-03-23

Study Completion Date

2019-11-22

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

To determine if MRI can detect preoperative invasion of cartilage by laryngeal and hypopharyngeal carcinoma, and to compare it to CT imaging and histopathology in excised larynges and/or hypopharynges.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

MRI Laryngeal Imaging With a Surface Coil

NCT00965003

Laryngeal Neoplasms Head and Neck Cancers Larynx Cancer

TERMINATED EARLY_PHASE1

FArial NErf MRI in the Preoperative Assessment of PArotide Tumors

NCT04613349

Parotid Tumor

RECRUITING

Functional ImaGing of Heterogeneity in Head and Neck Tumors - Validation From Surgical Specimens

NCT03160495

Squamous Cell Carcinoma of the Head and Neck

COMPLETED

Use of Multiparametric MRI in the Management of Head and Neck Cancer: a Prospective Analysis

NCT03993665

Head and Neck Cancer Multiparametric MRI Cervical Lymph Node +3 more

ACTIVE_NOT_RECRUITING

MRI Mapping in Planning Radiation Therapy to the Base of Skull and Brain in Patients With Nonmetastatic Head and Neck Cancer

NCT00984074

Head and Neck Cancer

COMPLETED

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Hypopharyngeal Carcinoma Laryngeal Carcinoma

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Pharyngo laryngeal MRI

Patient with a laryngeal or hypopharyngeal cancer at any stage, with a doubt about cartilage invasion and eligible for surgical treatment for which there is an indication for performing an MRI in addition to CT at the discretion of the investigator

Pharyngo laryngeal MRI

Intervention Type OTHER

Patients will be outgoing a pharyngolaryngeal MRI, with injection of gadolinium, in addition to the CT imaging. They will have this MRI in case of doubt about cartilage invasion. It will be realised during the time between the CT imaging and the day of surgery.

Device : gadolinium-based MRI contrast agent This will be realized according to the standard procedure.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Pharyngo laryngeal MRI

Patients will be outgoing a pharyngolaryngeal MRI, with injection of gadolinium, in addition to the CT imaging. They will have this MRI in case of doubt about cartilage invasion. It will be realised during the time between the CT imaging and the day of surgery.

Device : gadolinium-based MRI contrast agent This will be realized according to the standard procedure.

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Patient ≥18 years old
* Patient with a laryngeal or hypopharyngeal cancer at any stage
* Patient eligible for a surgical treatment in multidisciplinary consultation
* Patient who did not oppose its participation to the study
* Indication for performing an MRI in addition to CT at the discretion of the investigator

Exclusion Criteria

* Patient with an ASA ("American Society of Anesthesiologists", international anesthesia classification) score ≥ 3,
* Patient with a chirurgical contraindication
* Patient with a MRI contraindication
* Pregnant or nursing woman
* Adult requiring protection (guardianship, supervision)
* Patient participating in interventional research (Excluding physiological studies and interventional research involving only minimal risks and constraints that do not interfere with the analysis of the primary outcome).

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No