Prospective, Single-Center, Non-Randomized Study of the PhysioWave™ Cardiovascular Analyzer

NCT ID: NCT03126994

Last Updated: 2018-08-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

160 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-04-11

Study Completion Date

2017-05-19

Brief Summary

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This is a prospective, single-center, non-randomized validation study being conducted under a non-significant risk study design with the primary aim to evaluate PWV, PR, and BW accuracy in a sample of subjects representative of the US general adult population. The primary study objective is to demonstrate equivalency when measuring: Pulse Wave Velocity (PWV) and Pulse Rate (PR) between the PhysioWave Cardiovascular Analyzer (CA) and AtCor Medical SphygmoCor® XCEL PWA \& PWV (XCEL), and Body Weight (BW) between the CA and the Detecto Solo Digital Healthcare Scale (Detecto).

Detailed Description

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Conditions

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Cardiovascular Risk Factor

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Prospective validation study to evaluate PWV, PR, and BW accuracy in a sample of subjects representing the US general adult population.
Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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PhysioWave Cardiovascular Analyzer

The Experimental Device is the PhysioWave Cardiovascular Analyzer, which will be used to measure Pulse Wave Velocity, Pulse Rate, Body Weight, and BMI. This will be compared to FDA-cleared devices to determine equivalence: AtCor XCEL PWA \& PWV to measure Pulse Wave Velocity and Pulse rate, and Detecto SOLO to measure Body Weight and BMI.

Group Type EXPERIMENTAL

PhysioWave Cardiovascular Analyzer

Intervention Type DEVICE

Measurement of Pulse Wave Velocity, Pulse Rate, Body Weight and BMI

AtCor XCEL PWA & PWV

Intervention Type DEVICE

Measurement of Pulse Wave Velocity and Pulse Rate

Detecto SOLO

Intervention Type DEVICE

Measurement of Body Weight and BMI

Interventions

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PhysioWave Cardiovascular Analyzer

Measurement of Pulse Wave Velocity, Pulse Rate, Body Weight and BMI

Intervention Type DEVICE

AtCor XCEL PWA & PWV

Measurement of Pulse Wave Velocity and Pulse Rate

Intervention Type DEVICE

Detecto SOLO

Measurement of Body Weight and BMI

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Subjects \>18 years old
* Subject signs a written Informed Consent form to participate in the study, prior to any study procedures


* Subject has been taking ACE Inhibitors or Angiotensin Receptor Blockers for at least 30 days

Exclusion Criteria

* Known significant carotid or femoral artery stenosis
* Non-palpable (non-detectable) arterial pulse at the sites of measurements
* Pacemaker, defibrillator, or other cardiac stimulator
* Erratic, accelerated or mechanically controlled irregular heart rhythm, or an arrhythmia
* History of cardiac valve disorder or cardiac valve disease
* History of venous disease, including venous insufficiency or deep vein thrombosis
* History of peripheral artery disease
* Requirement for supplemental oxygen
* Neuromuscular disorders that cause shaking or tremors (such as Parkinson's disease or Multiple Sclerosis), or other disease or condition affecting balance
* Amputation or malformation of any limb or extremity (foot, leg, or arm) which would impede the placement of blood pressure cuffs or standing on the scale with two feet.
* Known or suspected pregnancy
* Inability to provide informed consent
* Mental incompetence or a prisoner status
* Current participation in a clinical trial of another investigational drug or device in which the study endpoint has not been met
* BMI \> 40
* Subjects \> 400 lbs
* Subjects on strong vasoactive drugs, such as those used to control high blood pressure, for \<30 days
* Blood loss or blood donation of ˃ 550 mL within 30 days before study procedure
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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PhysioWave, Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Diablo Clinical Research

Walnut Creek, California, United States

Site Status

Countries

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United States

Other Identifiers

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780-00033

Identifier Type: -

Identifier Source: org_study_id

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