Acute-phase Response & Periodontal Treatment in Obese Patients
NCT ID: NCT03122977
Last Updated: 2022-11-03
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
38 participants
INTERVENTIONAL
2016-06-01
2021-10-01
Brief Summary
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Detailed Description
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The aim of this study is to compare quadrant scaling and root planing (Q-SRP) versus full-mouth treatment (FM-SRP) in terms of acute-phase responses following non surgical periodontal treatment.
Treatment will be provided using both hand and ultrasonic instrumentation with fine tips.
FM-SRP patients will received treatment within 24 h. Q-SRP patients will received four quadrants sessions of periodontal treatment with an interval of 1 week between sessions.
Vital, endothelial function and blood inflammatory parameters will be evaluated at baseline, 24 hours after the first treatment and after 3 months. Periodontal parameters will be evaluated at baseline and after 3 months.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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Full mouth scaling and root planing
FM-SRP Non surgical periodontal treatment will be performed in all dentition within 24 hours
FM-SRP
Supra- and sub-gingival mechanical instrumentation of the root surface of the whole dentition within 24 hours.
Quadrant scaling and root planing
Q-SRP Non surgical periodontal treatment will be performed in all dentition subdivided in four appointments. Each appointment will be performed in one week interval. In each appointment only a "quadrant" of the dentition will be instrumented.
Q-SRP
Supra- and sub-gingival mechanical instrumentation of the root surface will be performed in all dentition subdivided in four appointments. Each appointment will be performed in one week interval. In each appointment only a "quadrant" of the dentition will be instrumented.
Interventions
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FM-SRP
Supra- and sub-gingival mechanical instrumentation of the root surface of the whole dentition within 24 hours.
Q-SRP
Supra- and sub-gingival mechanical instrumentation of the root surface will be performed in all dentition subdivided in four appointments. Each appointment will be performed in one week interval. In each appointment only a "quadrant" of the dentition will be instrumented.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* 20% of periodontal pockets of the entire dentition
* 20% bleeding on probing of the entire dentition
* documented radiographic bone loss
* diagnosis of Obesity as measured through Body Mass Index (BMI) superior than 30
Exclusion Criteria
* pregnant or lactating females
* need of antibiotic coverage for periodontal treatment
* treatment with statin and/or acetylsalicylic acid
* BMI \> 35
18 Years
80 Years
ALL
No
Sponsors
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University of Pisa
OTHER
Responsible Party
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Filippo Graziani, DDS MClinDent PhD
Professor of Periodontology
Principal Investigators
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Filippo Graziani, DDS, PhD
Role: PRINCIPAL_INVESTIGATOR
University of Pisa
Locations
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University Hospital of Pisa
Pisa, , Italy
Countries
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Other Identifiers
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3399/11_B
Identifier Type: -
Identifier Source: org_study_id
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