Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
100 participants
OBSERVATIONAL
2018-04-24
2020-01-30
Brief Summary
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Detailed Description
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To more accurately measure the amount of carbohydrates, fats and proteins that the body is metabolizing, participants will be asked to provide two urine samples (one at the beginning, and one at the end, of the study).
To determine what version of ApoE the participant inherited, the investigator will conduct a genetic test on DNA isolated from the participant's blood.
Conditions
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Study Design
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COHORT
PROSPECTIVE
Interventions
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Resting State Indirect Calorimetry
The investigator will measure the amount of oxygen participants breathe in and the amount of carbon dioxide they breathe out using a portable unit. Participants will be asked wearing a loose-fitting face mask that measures oxygen intake and carbon dioxide output.
ApoE
The investigator will conduct a genetic test on DNA isolated from from the participants blood. Participants will be asked to provide about 2 tablespoons.
Metabolism
To more accurately measure the amount of carbohydrates, fats and proteins that the participants bodies metabolize, participants will be asked to provide two urine samples (one at the beginning, and one at the end, of the study). The total amount of urine to be collected is approximately 4 teaspoons.
Cognitive Challenge
Participants will be asked to follow simple instructions that are displayed on computer screen.
Eligibility Criteria
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Inclusion Criteria
* ages 18-65
* cognitively normal
* good health
Exclusion Criteria
* have a bleeding disorder,
* have a history of stroke, seizures, Parkinson's disease, history of head injury with loss of consciousness, or other dementing disorder.
* have a history of alcoholism or drug abuse
* have a history of schizophrenia or currently suffer from bipolar disorder or major depression.
* have vision or hearing loss severe enough to interfere with cognitive testing
18 Years
65 Years
ALL
No
Sponsors
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Lance Johnson
OTHER
Responsible Party
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Lance Johnson
Principal Investigator
Principal Investigators
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Lance Johnson1, PhD
Role: PRINCIPAL_INVESTIGATOR
University of Kentucky
Locations
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University of Kentucky Medical Center
Lexington, Kentucky, United States
Countries
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Other Identifiers
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17-0202-F1G
Identifier Type: -
Identifier Source: org_study_id
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