Effectiveness of Probiotic Supplementation on Crying Time in Infantile Colic

NCT ID: NCT03106285

Last Updated: 2022-05-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

WITHDRAWN

Clinical Phase

NA

Study Classification

INTERVENTIONAL

Study Start Date

2017-04-14

Study Completion Date

2019-07-01

Brief Summary

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This study aims to investigate the effectiveness of Lactobacillus reuteri DSM17938 supplementation on infantile colic in Indonesian infants.

Detailed Description

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Infantile colic is a problem faced by many parents and caregivers. There is no evidence that medications does help in this situation. The etiology of infantile colic is still unknown.

Lactobacillus reuteri has been shown in five studies to reduce crying time in infants diagnosed with infantile colic.

Conditions

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Colic, Infantile

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

TRIPLE

Participants Caregivers Investigators

Study Groups

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Lactobacillus reuteri DSM17938

Oil drops

Group Type EXPERIMENTAL

Lactobacillus reuteri DSM17938

Intervention Type DIETARY_SUPPLEMENT

5 drops of active oil drops. The active dose consists of 10\^8 CFU L retueri DSM17938

Placebo

Oils drops

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type DIETARY_SUPPLEMENT

5 drops of placebo drops

Interventions

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Lactobacillus reuteri DSM17938

5 drops of active oil drops. The active dose consists of 10\^8 CFU L retueri DSM17938

Intervention Type DIETARY_SUPPLEMENT

Placebo

5 drops of placebo drops

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* otherwise healthy infants
* Infantile colic according to Roe IV criteria
* Full term infants
* Birth weight 2500 - 4000g
* Exclusively breast milk or partially breastfed
* Mothers last education degree is Senior high school

Exclusion Criteria

* Clinically suspected allergy
* Consumption of probiotics, antibiotics, PPI
* Failure to thrive
Maximum Eligible Age

3 Months

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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BioGaia AB

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Badriul Hegar, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

RSCM, Rumah Sakit Cipto Mangunkusumo. University of Indonesia

Locations

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Badriul Hegar

Jakarta, , Indonesia

Site Status

Countries

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Indonesia

Other Identifiers

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CSUB0130

Identifier Type: -

Identifier Source: org_study_id

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