Control of Colic in Infants by Dietary Supplementation With the Probiotic Lactobacillus Reuteri

NCT ID: NCT01067027

Last Updated: 2011-06-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE4

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-06-30

Study Completion Date

2012-06-30

Brief Summary

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It is believed that probiotic Lactobacillus reuteri will improve the symptoms of breast-fed infants with colic.

Detailed Description

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Conditions

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Colic

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Interventions

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Lactobacillus reuteri

5 drops of study product 30 minutes before feeding.

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* Ifants aged between 14 and 60 days
* Breast fed, exclusively during length of trial
* Diagnosis of infantile colic according to Wessel's criteria i.e paroxysmal fussing in infancy for more than three hours per day, at least three days per week.
* Debut of colic symptoms 6+/-1 days before randomization
* Gestational age between 37 and 42 weeks
* Apgar score higher than 7 at 5 minutes
* Mothers willing to follow a cows mild-free diet (free from mild, yoghurt, cheese etc) during the study period
* Written informed consent from one or both parents
* Stated availability throughout the study period

Exclusion Criteria

* Major chronic disease
* Administration of anitbiotics the week before randomization
* Administration of probiotics the week before randomization
* Participation in other clinical trials
Minimum Eligible Age

14 Days

Maximum Eligible Age

60 Days

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Children's Investigational Research Program, LLC

OTHER

Sponsor Role lead

Responsible Party

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Children's Investigational Research Program

Principal Investigators

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Bryan M Harvey, M.D.

Role: PRINCIPAL_INVESTIGATOR

Children's Investigational Research Program

Locations

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Children's Investigational Research Program

Bentonville, Arkansas, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Misty R Ross, MA

Role: CONTACT

479-254-6772 ext. 21

Facility Contacts

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Misty R Ross, MA

Role: primary

479-254-6772 ext. 21

Tonya D Hogue, Coordinator

Role: backup

479-254-6772 ext. 22

Other Identifiers

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Colic001

Identifier Type: -

Identifier Source: org_study_id

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