Correspondence of Folate Dietary Intake and Biomarker Data

NCT ID: NCT03089684

Last Updated: 2017-03-24

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 4878 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2011-01-01
• Study Completion Date: 2012-12-31

Brief Summary

This NHANES analysis compares self-reported dietary folate with serum and red blood cell folate status in U.S. adults.

Detailed Description

Background: Public health concerns of both low and high folate status exist in the U.S. Recent publications have questioned the utility of self-reported dietary intake data in research and monitoring.

Objective: The purpose of this analysis was to examine the relationship between self-reported folate intakes and folate status biomarkers, and to evaluate their usefulness for several types of applications.

Design: Usual dietary intakes of folate were examined using the National Cancer Institute (NCI) method to adjust 2, 24-hour dietary recalls (including dietary supplements) for within-person variation and compared these intakes with serum and red blood cell (RBC) folate among 4,878 non-pregnant, non-lactating participants ≥19y in NHANES 2011-2012, a nationally representative, cross-sectional survey, with respect to consistency across prevalence estimates and rank order comparisons.

Conditions

Folate Deficiency

Study Design

• Observational Model Type: OTHER
• Study Time Perspective: OTHER

Interventions

No intervention

No intervention

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• adults, ages 19+ years

Exclusion Criteria

• missing data
• non-pregnant
• non-lactating

• Minimum Eligible Age: 19 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

National Institute of Health and Nutrition

OTHER_GOV

Sponsor Role: lead

Responsible Party

Regan Bailey

Nutritional Epidemiologist

Responsibility Role: PRINCIPAL_INVESTIGATOR

Other Identifiers

ODS2015_1

Identifier Type: -

Identifier Source: org_study_id