EVALUATION OF RESPIRATORY MECHANICS AND FUNCTIONALITY IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE

NCT ID: NCT03086590

Last Updated: 2018-11-07

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 20 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2016-11-01
• Study Completion Date: 2018-03-01

Brief Summary

To associate a lean mass, peripheral muscle strength, kinematic thoracic-abdominal, respiratory metabolic response, mobility and diaphragmatic thickness, verifying its relation with the obstruction level of COPD

Detailed Description

Individuals with COPD present restriction in their daily lives due to changes and bodily disorders promoted by the disease, such as changes in types of muscle fibers and chronic inflammatory process, causing a low level of physical activity and quality of life, besides being closely Related to the need for hospitalizations and increased mortality. A cross-sectional study with a convenience sample was performed at the Laboratory of Cardiopulmonary Physiotherapy of the Federal University of Pernambuco during the period from December 2016 to February 2018. As measurements of body composition were performed with a bio-balance scale, Evaluation of the peripheral muscle strength will be used the dynamometer, a load cell and electromyography, a kinematic thoracic-abdominal will be measured by optoelectronic plethysmography, a respiratory metabolic response will be verified during the 6-minute walk test using the gas analyzer, and for evaluation of mobility and diaphragmatic thickness are used on ultrasound associated with pneumotachograph.

Conditions

Pulmonary Disease, Chronic Obstructive

Study Design

• Observational Model Type: OTHER
• Study Time Perspective: CROSS_SECTIONAL

Study Groups

Group 1

COPD mild. The individuals allocated to this group have FEV1 ≥ 80% predicted.

No interventions assigned to this group

Group 2

COPD Moderate. The individuals allocated to this group have 50% ≤ FEV1 \< 80% predicted.

No interventions assigned to this group

Group 3

COPD Severe. The individuals allocated to this group have 30% ≤ FEV1 \< 50% predicted.

No interventions assigned to this group

Group 4

COPD Very severe. The individuals allocated to this group have FEV1 \< 30% predicted.

No interventions assigned to this group

Eligibility Criteria

Inclusion Criteria

• Young adults, adults and elderly subjects

Exclusion Criteria

• Others respiratory diseases;
• Heart diseases;
• Those who are in some previous training program or rehabilitation;

• Minimum Eligible Age: 21 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Universidade Federal de Pernambuco

OTHER

Sponsor Role: lead

Responsible Party

Rodrigo Viana Correia de Souza

Principal Investigator

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Universidade Federal de Pernambuco

Recife, Pernambuco, Brazil

Countries

Brazil

Other Identifiers

UFPE-M1

Identifier Type: -

Identifier Source: org_study_id