Efficacy and Safety of Xuesaitong Soft Capsule for Coronary Heart Disease Unstable Angina

NCT ID: NCT03083119

Last Updated: 2017-03-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE2

Total Enrollment

70 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-03-20

Study Completion Date

2017-08-20

Brief Summary

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In this study, typical cases of coronary heart disease are selected. They will be intervened by Xuesaitong soft capsules to investigate efficacy and safety for Coronary Heart disease.

Detailed Description

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Conditions

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Coronary Heart Disease Unstable Angina

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

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Xuesaitong soft capsule group

Patients who confirmed by coronary angiography and diagnosed blood stasis syndrome of coronary heart disease are given conventional Western medicine treatment and Xuesaitong soft capsule.

Group Type EXPERIMENTAL

Xuesaitong soft capsule

Intervention Type DRUG

Panax Notoginseng Saponins, Specification:0.33 per bag, once take two pills and twice a day during a month.

Placebo Comparator

Patients who confirmed by coronary angiography and diagnosed blood stasis syndrome of coronary heart disease are given conventional Western medicine treatment and placebo.

Group Type PLACEBO_COMPARATOR

Placebo oral capsule

Intervention Type DRUG

Xuesaitong soft capsule Placebo, soft capsule, once take two pills and twice a day during a month.

Interventions

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Xuesaitong soft capsule

Panax Notoginseng Saponins, Specification:0.33 per bag, once take two pills and twice a day during a month.

Intervention Type DRUG

Placebo oral capsule

Xuesaitong soft capsule Placebo, soft capsule, once take two pills and twice a day during a month.

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Clinical diagnosis of coronary angiography unstable angina
* Clinical diagnosis of unstable angina
* Age of 30 to 75 years old
* Not use thrombolysis, dilate coronary drugs within two weeks
* Sign the consent

Exclusion Criteria

* Severe valvular heart disease
* Insulin-dependent diabetes
* mental disease
* Combined with severe liver, kidney, hematopoietic system disorder
* Patients with malignant tumors
* Pregnancy or breast-feeding women
* Recent history of trauma
* Drug allergy
Minimum Eligible Age

30 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Jie Wang

OTHER

Sponsor Role lead

Responsible Party

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Jie Wang

Guang'anmen Hospital of China Academy of Chinese Medical Sciences

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Jie Wang

Role: PRINCIPAL_INVESTIGATOR

Guang Anmen Hospital

Locations

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Guang Anmen Hospital

Beijing, Beijing Municipality, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Lian Duan

Role: CONTACT

+8601088001817

Facility Contacts

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Lian Duan

Role: primary

+8601088001817

References

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Duan L, Liu Y, Li J, Zhang Y, Dong Y, Liu C, Wang J. Panax notoginseng Saponins Alleviate Coronary Artery Disease Through Hypermethylation of the miR-194-MAPK Pathway. Front Pharmacol. 2022 Jun 16;13:829416. doi: 10.3389/fphar.2022.829416. eCollection 2022.

Reference Type DERIVED
PMID: 35784716 (View on PubMed)

Other Identifiers

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81473561

Identifier Type: -

Identifier Source: org_study_id

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