Mobile Enhancement of Motivation in Schizophrenia

NCT ID: NCT03059771

Last Updated: 2018-07-30

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 59 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2017-02-28
• Study Completion Date: 2018-01-16

Brief Summary

Motivation deficits are a strong determinant of poor functional outcomes in people with schizophrenia. Mobile interventions are a promising approach to improving these deficits, as they can provide frequent cues and reinforcements that support goal-directed behavior. The primary aims of this study are to conduct a pilot study using a randomized design to 1) Test the feasibility and acceptability of a personalized mobile text message intervention, Mobile Enhancement of Motivation in Schizophrenia (MEMS) and to 2) Test the preliminary effectiveness of MEMS compared to a control condition.

Detailed Description

Objectives: Motivation deficits are one of the strongest determinants of poor functional outcomes in people with schizophrenia. Mobile interventions are a promising approach to improving these deficits, as they can provide frequent cues and reinforcements that support goal-directed behavior. The objective of this study is to conduct a pilot study using a randomized design to 1) Test the feasibility and acceptability of a personalized mobile text message intervention, Mobile Enhancement of Motivation in Schizophrenia (MEMS) and to 2) Test the preliminary effectiveness of MEMS compared to a control condition. Methods: Up to forty outpatients with a schizophrenia-spectrum disorder will be recruited. All participants will set individualized recovery goals to complete over an eight-week period; those randomized to receive MEMS will also receive three sets of personalized, interactive text messages each weekday to reinforce and cue goal completion. Before and after the eight-week period, participants in both groups will complete validated measures of motivation. Both groups will also report their goal attainment after eight weeks. Results: It is anticipated that those in the MEMS group will demonstrate greater goal attainment and improvements in motivation compared to the control group. Discussion: This project will test the initial feasibility, acceptability, and effectiveness of a novel intervention for improving one of the most debilitating aspects of schizophrenia.

Conditions

Schizophrenia; Schizo Affective Disorder; Psychosis

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: SINGLE

Study Groups

Mobile Enhancement of Motivation (MEMS)

Facilitators will first collaboratively help participants set personal recovery-goals using Collaborative Goal Technology (Clarke et al., 2006). Participants will then receive three sets of interactive text messages each weekday for eight weeks to reinforce and cue goal completion.

Group Type: EXPERIMENTAL

Mobile Enhancement of Motivation (MEMS)

Intervention Type: BEHAVIORAL

The MEMS group will engage in a goal-setting session and then receive personalized text-messages to support goal attainment.

Control

Participants will only engage in a goal-setting session where facilitators will collaboratively help participants set personal recovery-goals using Collaborative Goal Technology (Clarke et al., 2006).

Group Type: ACTIVE_COMPARATOR

Control

Intervention Type: BEHAVIORAL

The control group will only engage in a goal-setting session.

Interventions

Mobile Enhancement of Motivation (MEMS)

The MEMS group will engage in a goal-setting session and then receive personalized text-messages to support goal attainment.

Intervention Type: BEHAVIORAL

Control

The control group will only engage in a goal-setting session.

Intervention Type: BEHAVIORAL

Eligibility Criteria

Inclusion Criteria

• Schizophrenia-spectrum diagnosis
• Have a text-message enabled cell-phone
• Are a current client at a participating community mental health center
• Are in a non-acute phase of illness or have no medication changes or hospitalizations in the prior 30 days
• Demonstrate a minimum of moderate motivation impairments according to the Clinical Assessment Interview for Negative Symptoms (CAINS; Kring et al., 2013)
• Have an English reading level at or above the fourth grade according to the Graded Word List (Pray & Ross, 1969)

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Indiana Clinical and Translational Sciences Institute

OTHER

Sponsor Role: collaborator

American Psychological Foundation

OTHER

Sponsor Role: collaborator

Indiana University-Purdue University Indianapolis Department of Psychology

UNKNOWN

Sponsor Role: collaborator

Indiana University

OTHER

Sponsor Role: lead

Responsible Party

Michelle Salyers

Professor and Director of Clinical Psychology

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Midtown Community Mental Health Center

Indianapolis, Indiana, United States

Countries

United States

References

Luther L, Fischer MW, Johnson-Kwochka AV, Minor KS, Holden R, Lapish CL, McCormick B, Salyers MP. Mobile enhancement of motivation in schizophrenia: A pilot randomized controlled trial of a personalized text message intervention for motivation deficits. J Consult Clin Psychol. 2020 Oct;88(10):923-936. doi: 10.1037/ccp0000599. Epub 2020 Aug 13.

Reference Type: DERIVED

PMID: 32790451 (View on PubMed)

Other Identifiers

1701070796

Identifier Type: -

Identifier Source: org_study_id