Concurrent Chemotherapy for Elderly Patients With Locoregionally Advanced Nasopharyngeal Carcinoma

NCT ID: NCT03058432

Last Updated: 2017-02-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE2

Total Enrollment

122 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-01-31

Study Completion Date

2019-12-31

Brief Summary

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Concurrent Chemotherapy for Elderly Patients With Locoregionally Advanced Nasopharyngeal Carcinoma

Detailed Description

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To evaluate concurrent chemotherapy for elderly patients with locoregionally advanced nasopharyngeal carcinoma treated by intensity-modulated radiotherapy

Conditions

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Nasopharyngeal Carcinoma

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Concurrent cisplatin based chemoradiotherapy versus radiotherapy alone
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Intensity-modulated Radiotherapy

Radiotherapy alone was given.

Group Type EXPERIMENTAL

Radiotherapy alone

Intervention Type RADIATION

Concurrent chemoradiotherapy

Concurrent cisplatin-based radiotherapy was given.

Group Type ACTIVE_COMPARATOR

Concurrent chemoradiotherapy

Intervention Type RADIATION

Interventions

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Radiotherapy alone

Intervention Type RADIATION

Concurrent chemoradiotherapy

Intervention Type RADIATION

Eligibility Criteria

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Inclusion Criteria

* Previously untreated and histologically confirmed locoregionally advanced nasopharyngeal carcinoma

Exclusion Criteria

* A history of another invasive cancer, prior RT to the head and neck area, prior cytotoxic chemotherapy or anti-EGFR therapy or the presence of any serious medical conditions,supposed to live less than 6 months.
Minimum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Zhejiang Cancer Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Xiaozhong Chen

Hangzhou, Zhejiang, China

Site Status RECRUITING

Countries

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China

Facility Contacts

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Xiaozhong Chen, MD

Role: primary

+86-571-88128202

Other Identifiers

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ZJCH-2016-HN03

Identifier Type: -

Identifier Source: org_study_id

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