The Effect of Pessary Post Vaginal Prolapse Repair, for One Month, to Reduce the Recurrence Rate of Prolapse

NCT ID: NCT03056586

Last Updated: 2017-03-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-03-20

Study Completion Date

2019-12-20

Brief Summary

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Genital prolapse is a common complain. 30-40% of women will complain of uterine prolapse or cystocele or rectocele, or mixed. About half of them will require surgical repair for the prolapse, with or without hysterectomy. Of these patients about 30-40% will have recurrence of the prolapse, which in some cases requires second operation.

In this study the investigators want to investigate whether a vaginal pessary inserting in the end of the primary surgery, for 4 weeks, will reduce the recurrence rate.

Detailed Description

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All patients going for vaginal surgery for genital prolapse, stage 3-4, with cystocele, rectocele or uterine cervix prominent from the vagina. These patients, after signing an informed consent, a vaginal pessary will insert at the end of the operation and will stay for 4 weeks post-op.

After 4 weeks the pessary will be removed, and the patient will followed for 2 years, for recurrence of prolapse.

Conditions

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Use of Pessary Reduce the Number of Prolapse Recurrence Uterine Prolapse Cystocele Rectocele

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

SINGLE

Participants

Study Groups

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1. study group

100 patients who agree to participate in the study, will be operate according to our protocol for pelvic organ prolapse. At the end of the operation a vaginal pessary will be inserted and suture to the vaginal walls for a 4 week period.

Follow-up will be after 3, 6, and 12 month period.

Group Type EXPERIMENTAL

vaginal pessary

Intervention Type DEVICE

A vaginal pessary will be inserted at the end of the operation, for genital prolapse, and will be sutured to the vaginal wall. The pessary will stay in the vagina for 4 weeks.

2. control

100 Women who will refuse to participate in the study, will agree to be follow-up by our team for 3, 6, and 12 month post operative.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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vaginal pessary

A vaginal pessary will be inserted at the end of the operation, for genital prolapse, and will be sutured to the vaginal wall. The pessary will stay in the vagina for 4 weeks.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* all healthy patients with genital prolapse grade 3-4, going for vaginal surgery
* age 30-80years

Exclusion Criteria

* patients with pelvic inflammatory disease
* patients after pelvic irradiation
* large vaginal erosion
* vaginal bleeding uncontrolled or undiagnosed
* patients going for surgery with mesh
Minimum Eligible Age

30 Years

Maximum Eligible Age

80 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Meir Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Klein zvi

Head of urogynecology unit

Responsibility Role PRINCIPAL_INVESTIGATOR

Other Identifiers

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0188-16-MMC

Identifier Type: -

Identifier Source: org_study_id

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