Long-term Quality of Life of Patients With a Congenital Heart Disease, Treated by Surgery in Adulthood at the Brugmann Hospital.

NCT ID: NCT03050112

Last Updated: 2017-11-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

250 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-02-14

Study Completion Date

2017-06-01

Brief Summary

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Adults with a congenital heart disease, having undergone a surgical intervention or a re-do surgery in adulthood, are a growing group of subjects in the general population. This increase is explained by improved medical and surgical techniques, with a better survival rate as outcome.

There is nowadays a growing interest in the quality of life of this group of subjects. However, studies give contradictory results. This can be explained on one hand by the vast majority of pathologies within this population, and on the other hand by the absence of a cardio-specific tool for quality of life measurement.

The MacNew questionnaire is cardio-specific. It allows an evaluation of the quality of life based on the exploration of three domains: physical, emotional and social.

The aim of this study is:

* to evaluate the quality of life of these patients, by using the MacNew questionnaire
* to explore the needs in terms of prevention, treatment and multi-disciplinary follow-up
* to assess the mortality within this group of patients.

Detailed Description

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Conditions

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Congenital Heart Disease

Keywords

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MacNew questionnaire Quality of life

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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Congenital cardiopathy

Patients having had surgery in adulthood for a congenital heart disease, at the Brugmann University Hospital. The group consists in patients aged 16 years or older, having had surgery between 01/01/1998 and 31/12/2015.

Group Type EXPERIMENTAL

MacNew questionnaire

Intervention Type OTHER

Patients will be asked to fill in the MacNew questionnaire on quality of life (phone contact).

Interventions

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MacNew questionnaire

Patients will be asked to fill in the MacNew questionnaire on quality of life (phone contact).

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

Patients having had surgery in adulthood for a congenital heart disease, at the Brugmann University Hospital. The group consists in patients aged 16 years or older, having had surgery between 01/01/1998 and 31/12/2015

Exclusion Criteria

None
Minimum Eligible Age

16 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Pierre Wauthy

OTHER

Sponsor Role lead

Responsible Party

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Pierre Wauthy

Head of clinic

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Halit Ozel

Role: PRINCIPAL_INVESTIGATOR

CHU Brugmann

Pierre Wauthy, MD

Role: STUDY_DIRECTOR

CHU Brugmann

Locations

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CHU Brugmann

Brussels, , Belgium

Site Status

Countries

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Belgium

References

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Wauthy P, Massaut J, Sanoussi A, Demanet H, Morissens M, Damry N, Dessy H, Malekzadeh-Milani SG, Deuvaert FE. Ten-year experience with surgical treatment of adults with congenital cardiac disease. Cardiol Young. 2011 Feb;21(1):39-45. doi: 10.1017/S1047951110001332. Epub 2010 Oct 6.

Reference Type BACKGROUND
PMID: 20923595 (View on PubMed)

Lane DA, Lip GY, Millane TA. Quality of life in adults with congenital heart disease. Heart. 2002 Jul;88(1):71-5. doi: 10.1136/heart.88.1.71.

Reference Type BACKGROUND
PMID: 12067950 (View on PubMed)

Immer FF, Althaus SM, Berdat PA, Saner H, Carrel TP. Quality of life and specific problems after cardiac surgery in adolescents and adults with congenital heart diseases. Eur J Cardiovasc Prev Rehabil. 2005 Apr;12(2):138-43. doi: 10.1097/01.hjr.0000159318.62466.dc.

Reference Type BACKGROUND
PMID: 15785299 (View on PubMed)

Fteropoulli T, Stygall J, Cullen S, Deanfield J, Newman SP. Quality of life of adult congenital heart disease patients: a systematic review of the literature. Cardiol Young. 2013 Aug;23(4):473-85. doi: 10.1017/S1047951112002351. Epub 2013 Feb 6.

Reference Type BACKGROUND
PMID: 23388149 (View on PubMed)

Apers S, Luyckx K, Moons P. Quality of life in adult congenital heart disease: what do we already know and what do we still need to know? Curr Cardiol Rep. 2013 Oct;15(10):407. doi: 10.1007/s11886-013-0407-x.

Reference Type BACKGROUND
PMID: 23955787 (View on PubMed)

Hofer S, Lim L, Guyatt G, Oldridge N. The MacNew Heart Disease health-related quality of life instrument: a summary. Health Qual Life Outcomes. 2004 Jan 8;2:3. doi: 10.1186/1477-7525-2-3.

Reference Type BACKGROUND
PMID: 14713315 (View on PubMed)

Pavy B, Iliou MC, Hofer S, Verges-Patois B, Corone S, Aeberhard P, Curnier D, Henry J, Ponchon-Weess A, Oldridge N. Validation of the French version of the MacNew heart disease health-related quality of life questionnaire. Arch Cardiovasc Dis. 2015 Feb;108(2):107-17. doi: 10.1016/j.acvd.2014.09.006. Epub 2014 Nov 12.

Reference Type BACKGROUND
PMID: 25453715 (View on PubMed)

Dixon T, Lim LL, Oldridge NB. The MacNew heart disease health-related quality of life instrument: reference data for users. Qual Life Res. 2002 Mar;11(2):173-83. doi: 10.1023/a:1015005109731.

Reference Type BACKGROUND
PMID: 12018740 (View on PubMed)

Other Identifiers

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CHUB-QOL cardiopathy

Identifier Type: -

Identifier Source: org_study_id