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Study of Arterial Recanalization of the Central Retinal Artery Occlusions

NCT ID: NCT03049514

Last Updated: 2022-04-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

80 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-12-23

Study Completion Date

2022-04-02

Brief Summary

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Central retinal artery occlusions (CRAO) are the equivalent of an ischemic stroke (IS) at the retinal level. They share the same risk factors and common pathology. Their incidence is lower (8.5 / 100,000) and the functional prognosis is unfavorable in 80% of cases with visual acuity (VA) \<1/10. The diagnosis of an CRAO is clinically based on the sudden occurrence of a decrease in deep visual acuity with fundamentally signs of reactive ischemia. There is no data on early retinal arterial recanalization after CRAO, nor on the relationship between early recanalization (spontaneous or post-thrombolysis) and visual prognosis.

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Detailed Description

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Conditions

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Central Retinal Artery Occlusion

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Central Retinal Artery Occlusion ≤ 24 hours

Exclusion Criteria

* Retinal Dynamic angiography not performed within 48 hours of onset of symptoms
* Occlusion of a branch of the central retinal artery
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Fondation Ophtalmologique Adolphe de Rothschild

NETWORK

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Michaël Obadia, MD

Role: PRINCIPAL_INVESTIGATOR

Fondation A de Rothschild

Locations

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Fondation ophtalmique Adolphe de Rothschild

Paris, , France

Site Status

Countries

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France

References

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Abdelmassih Y, Mauget-Faysse M, Seners P, Milea D, Hallali G, Guillaume J, Lecler A, Vignal C, Le Mer Y, Paques M, Bonnin S, Obadia M. Early reperfusion in patients with acute retinal artery occlusion: A multicenter prospective study. Int J Stroke. 2025 Mar;20(3):338-346. doi: 10.1177/17474930241306692. Epub 2024 Dec 24.

Reference Type DERIVED
PMID: 39614619 (View on PubMed)

Other Identifiers

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MOA_2016_22

Identifier Type: -

Identifier Source: org_study_id

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