Giomer vs Glass Ionomer Cement for ART Occlusoproximal Restorations: a Randomized Clinical Trial

NCT ID: NCT02962713

Last Updated: 2021-03-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

182 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-11-06

Study Completion Date

2019-11-20

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Although the Atraumatic Restorative Treatment (ART) is well settled in the literature regarding occlusal-proximal cavities, the longevity of these restorations is still lower when compared to occlusal ones. This factor is often associated with low mechanical properties of glass ionomer cements (GIC). The objective of this randomized clinical trial is to evaluate the long-term cost-effectiveness of two different materials: an encapsulated GIC - Equia (GC Corp), compared with Giomer (Beautifill Bulk Restorative - Shofu) used as restoratives materials in occlusal-proximal ART restorations of primary molars. Children aged between 4 and 8 years, will be selected in schools in the city of Cerquilho, São Paulo. All restorations will be held following the precepts of the ART and the manufacturer's instructions. The restorations will be evaluated after 3, 6, 12, 18 and 24 months according to Roeleveld et al. (2006) criteria. To verify the survival of the restorations will be used Kaplan-Meier survival analysis and log rank test. To evaluate the association between the clinical variables, Cox regression test will be applied. For the cost analysis will be used analysis of variance. The level of significance for all tests will be considered to 5%.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Dental Caries

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

ART with Equia

Occlusal-proximal restoration in primary molars using Equia (Easy/Quick/Unique/Intelligent/Aesthetic) from GC Corp, encapsulated, pre-dosed and mechanized handling.

Group Type ACTIVE_COMPARATOR

ART with Equia

Intervention Type PROCEDURE

Occlusal-proximal ART restorations in primary molars using Equia (Easy/Quick/Unique/ Intelligent/Aesthetic) will be performed. No local anesthesia will be used. Infected carious tissue will be removed with hand instruments, and the cavities restored with GIC (Glass Ionomer Cement). The cavity will be filled with GIC. After the press-finger technique, the excess of material will be removed and occlusion will be checked.

ART with Giomer Beautifil-Bulk Restorative

Occlusal-proximal restoration in primary molars using Giomer Beautifil-Bulk Restorative (SHOFU Inc)

Group Type EXPERIMENTAL

ART with Giomer Beautifil-Bulk Restorative

Intervention Type PROCEDURE

Occlusal-proximal ART restorations in primary molars using Giomer will be performed. No local anesthesia will be used. Infected carious tissue will be removed with hand instruments, and the cavities restored with Giomer Beautifil-Bulk Restorative and occlusion will be checked.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

ART with Equia

Occlusal-proximal ART restorations in primary molars using Equia (Easy/Quick/Unique/ Intelligent/Aesthetic) will be performed. No local anesthesia will be used. Infected carious tissue will be removed with hand instruments, and the cavities restored with GIC (Glass Ionomer Cement). The cavity will be filled with GIC. After the press-finger technique, the excess of material will be removed and occlusion will be checked.

Intervention Type PROCEDURE

ART with Giomer Beautifil-Bulk Restorative

Occlusal-proximal ART restorations in primary molars using Giomer will be performed. No local anesthesia will be used. Infected carious tissue will be removed with hand instruments, and the cavities restored with Giomer Beautifil-Bulk Restorative and occlusion will be checked.

Intervention Type PROCEDURE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Children aging between 4 and 8 years
* Children presenting good health conditions
* Children whose parents or legal guardians accept and sign the consent form
* Children with at least one occlusal proximal caries lesion in primary molars
* only occlusal-proximal surfaces with caries lesions with dentin involvement

Exclusion Criteria

* severe behavioral issues
* presence of fistula or abscess near the selected tooth
* presence of pulp exposure in the selected tooth
* presence of mobility in the selected tooth
Minimum Eligible Age

4 Years

Maximum Eligible Age

8 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

University of Sao Paulo

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Daniela Prócida Raggio

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Daniela P Raggio, Professor

Role: PRINCIPAL_INVESTIGATOR

University of Sao Paulo

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

University of Sao Paulo

São Paulo, , Brazil

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Brazil

References

Explore related publications, articles, or registry entries linked to this study.

Walsh T, Worthington HV, Glenny AM, Appelbe P, Marinho VC, Shi X. Fluoride toothpastes of different concentrations for preventing dental caries in children and adolescents. Cochrane Database Syst Rev. 2010 Jan 20;(1):CD007868. doi: 10.1002/14651858.CD007868.pub2.

Reference Type BACKGROUND
PMID: 20091655 (View on PubMed)

van 't Hof MA, Frencken JE, van Palenstein Helderman WH, Holmgren CJ. The atraumatic restorative treatment (ART) approach for managing dental caries: a meta-analysis. Int Dent J. 2006 Dec;56(6):345-51. doi: 10.1111/j.1875-595x.2006.tb00339.x.

Reference Type BACKGROUND
PMID: 17243467 (View on PubMed)

ten Berge M, Hoogstraten J, Veerkamp JS, Prins PJ. The Dental Subscale of the Children's Fear Survey Schedule: a factor analytic study in The Netherlands. Community Dent Oral Epidemiol. 1998 Oct;26(5):340-3. doi: 10.1111/j.1600-0528.1998.tb01970.x.

Reference Type BACKGROUND
PMID: 9792126 (View on PubMed)

Takanashi Y, Penrod JR, Lund JP, Feine JS. A cost comparison of mandibular two-implant overdenture and conventional denture treatment. Int J Prosthodont. 2004 Mar-Apr;17(2):181-6.

Reference Type BACKGROUND
PMID: 15119869 (View on PubMed)

Sunico MC, Shinkai K, Katoh Y. Two-year clinical performance of occlusal and cervical giomer restorations. Oper Dent. 2005 May-Jun;30(3):282-9.

Reference Type BACKGROUND
PMID: 15986946 (View on PubMed)

Shimazu K, Oguchi R, Takahashi Y, Konishi K, Karibe H. Effects of surface reaction-type pre-reacted glass ionomer on oral biofilm formation of Streptococcus gordonii. Odontology. 2016 Sep;104(3):310-7. doi: 10.1007/s10266-015-0217-2. Epub 2015 Aug 30.

Reference Type BACKGROUND
PMID: 26319990 (View on PubMed)

Sheiham A. Dental caries affects body weight, growth and quality of life in pre-school children. Br Dent J. 2006 Nov 25;201(10):625-6. doi: 10.1038/sj.bdj.4814259.

Reference Type BACKGROUND
PMID: 17128231 (View on PubMed)

Sengul F, Gurbuz T. Clinical Evaluation of Restorative Materials in Primary Teeth Class II Lesions. J Clin Pediatr Dent. 2015 Summer;39(4):315-21. doi: 10.17796/1053-4628-39.4.315.

Reference Type BACKGROUND
PMID: 26161601 (View on PubMed)

Schriks MC, van Amerongen WE. Atraumatic perspectives of ART: psychological and physiological aspects of treatment with and without rotary instruments. Community Dent Oral Epidemiol. 2003 Feb;31(1):15-20. doi: 10.1034/j.1600-0528.2003.00021.x.

Reference Type BACKGROUND
PMID: 12542428 (View on PubMed)

Santamaria R, Innes N. Trial shows partial caries removal is an effective technique in primary molars. Evid Based Dent. 2014 Sep;15(3):81-2. doi: 10.1038/sj.ebd.6401044.

Reference Type BACKGROUND
PMID: 25343394 (View on PubMed)

Roeleveld AC, van Amerongen WE, Mandari GJ. Influence of residual caries and cervical gaps on the survival rate of Class II glass ionomer restorations. Eur Arch Paediatr Dent. 2006 Jun;7(2):85-91. doi: 10.1007/BF03320820.

Reference Type BACKGROUND
PMID: 17140533 (View on PubMed)

Raggio DP, Hesse D, Lenzi TL, Guglielmi CA, Braga MM. Is Atraumatic restorative treatment an option for restoring occlusoproximal caries lesions in primary teeth? A systematic review and meta-analysis. Int J Paediatr Dent. 2013 Nov;23(6):435-43. doi: 10.1111/ipd.12013. Epub 2012 Nov 28.

Reference Type BACKGROUND
PMID: 23190278 (View on PubMed)

Phantumvanit P, Songpaisan Y, Pilot T, Frencken JE. Atraumatic restorative treatment (ART): a three-year community field trial in Thailand--survival of one-surface restorations in the permanent dentition. J Public Health Dent. 1996;56(3 Spec No):141-5; discussion 161-3. doi: 10.1111/j.1752-7325.1996.tb02424.x.

Reference Type BACKGROUND
PMID: 8915959 (View on PubMed)

Oscarson N, Kallestal C, Fjelddahl A, Lindholm L. Cost-effectiveness of different caries preventive measures in a high-risk population of Swedish adolescents. Community Dent Oral Epidemiol. 2003 Jun;31(3):169-78. doi: 10.1034/j.1600-0528.2003.00033.x.

Reference Type BACKGROUND
PMID: 12752542 (View on PubMed)

Ngo HC, Mount G, Mc Intyre J, Tuisuva J, Von Doussa RJ. Chemical exchange between glass-ionomer restorations and residual carious dentine in permanent molars: an in vivo study. J Dent. 2006 Sep;34(8):608-13. doi: 10.1016/j.jdent.2005.12.012. Epub 2006 Mar 15.

Reference Type BACKGROUND
PMID: 16540227 (View on PubMed)

Miki S, Kitagawa H, Kitagawa R, Kiba W, Hayashi M, Imazato S. Antibacterial activity of resin composites containing surface pre-reacted glass-ionomer (S-PRG) filler. Dent Mater. 2016 Sep;32(9):1095-102. doi: 10.1016/j.dental.2016.06.018. Epub 2016 Jul 12.

Reference Type BACKGROUND
PMID: 27417376 (View on PubMed)

Mickenautsch S, Yengopal V, Banerjee A. Atraumatic restorative treatment versus amalgam restoration longevity: a systematic review. Clin Oral Investig. 2010 Jun;14(3):233-40. doi: 10.1007/s00784-009-0335-8. Epub 2009 Aug 18.

Reference Type BACKGROUND
PMID: 19688227 (View on PubMed)

Abanto J, Paiva SM, Sheiham A, Tsakos G, Mendes FM, Cordeschi T, Vidigal EA, Bonecker M. Changes in preschool children's OHRQoL after treatment of dental caries: responsiveness of the B-ECOHIS. Int J Paediatr Dent. 2016 Jul;26(4):259-65. doi: 10.1111/ipd.12192. Epub 2015 Sep 15.

Reference Type BACKGROUND
PMID: 26370072 (View on PubMed)

Amaral MT, Guedes-Pinto AC, Chevitarese O. Effects of a glass-ionomer cement on the remineralization of occlusal caries--an in situ study. Braz Oral Res. 2006 Apr-Jun;20(2):91-6. doi: 10.1590/s1806-83242006000200001.

Reference Type BACKGROUND
PMID: 16878198 (View on PubMed)

Anusavice KJ. Preservative dentistry: the standard of care for the 21st century. J Public Health Dent. 1995 Spring;55(2):67-8. doi: 10.1111/j.1752-7325.1995.tb02334.x. No abstract available.

Reference Type BACKGROUND
PMID: 7643329 (View on PubMed)

Bonifacio CC, Hesse D, de Oliveira Rocha R, Bonecker M, Raggio DP, van Amerongen WE. Survival rate of approximal-ART restorations using a two-layer technique for glass ionomer insertion. Clin Oral Investig. 2013 Sep;17(7):1745-50. doi: 10.1007/s00784-012-0859-1. Epub 2012 Oct 11.

Reference Type BACKGROUND
PMID: 23053709 (View on PubMed)

de Amorim RG, Leal SC, Frencken JE. Survival of atraumatic restorative treatment (ART) sealants and restorations: a meta-analysis. Clin Oral Investig. 2012 Apr;16(2):429-41. doi: 10.1007/s00784-011-0513-3. Epub 2011 Jan 28.

Reference Type BACKGROUND
PMID: 21274581 (View on PubMed)

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

GIOMERART

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.