Home Administration of NivestimTM in the Primary Prophylaxis of Chemotherapy-Induced Febrile Neutropenia

NCT ID: NCT02956967

Last Updated: 2019-02-11

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

171 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-09-23

Study Completion Date

2016-12-12

Brief Summary

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Non-interventional, non-comparative, national, multi-site, single-arm prospective observational study to investigate home administration of Nivestim in the primary prophylaxis of chemotherapy-Induced febrile neutropenia

Detailed Description

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Conditions

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Non-Interventional Study

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Patients receiving Nivestim

Overall satisfaction questionnaires of home use of Nivestim

Intervention Type OTHER

Interventions

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Overall satisfaction questionnaires of home use of Nivestim

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Male and female patients ≥ 18 years
* Declaration of informed consent signed by patient
* Patients with a solid tumour or with a malignant haematological tumour
* Patients who have been prescribed cytotoxic chemotherapy, irrespective of current cycle
* GCSF-naïve patients or patients pre-treated with GCSF who received no GCSF in the last three months before enrolment
* Patients starting primary prophylactic treatment using NivestimTM either to shorten the duration of a neutropenia or to prevent the occurrence of chemotherapy-induced FN

Exclusion Criteria

* Patients with chronic myeloid leukaemia (CML) or with myelodysplastic syndrome (MDS)
* Patients who are hypersensitive to one of the excipients of NivestimTM
* Patients not undergoing chemotherapy
* Patients being treated curatively or as secondary prophylaxis with G-CSF
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Pfizer

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Pfizer CT.gov Call Center

Role: STUDY_DIRECTOR

Pfizer

Locations

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Office of Manfred Welslau

Aschaffenburg, , Germany

Site Status

Office of Martine Klausmann

Aschaffenburg, , Germany

Site Status

Office of Bernhard Heinrich

Augsburg, , Germany

Site Status

Campus Charite Mitte, Med. Klinik m. Schwerpunkt Haematologie und Onkologie

Berlin, , Germany

Site Status

Office of Reinhard Musch

Berlin, , Germany

Site Status

Office of Peter Klare

Berlin, , Germany

Site Status

Office of Ute Bückner

Bochum, , Germany

Site Status

Office of Peter Jungberg

Chemnitz, , Germany

Site Status

Office of Ivo Azeh

Gelsenkirchen, , Germany

Site Status

Office of Peter von Wussow

Hanover, , Germany

Site Status

Office of Volker Petersen

Heidenheim, , Germany

Site Status

Office of Lars-Jörgen Hahn

Herne, , Germany

Site Status

Office of Michael Neise

Krefeld, , Germany

Site Status

Office of Gunther Rogmans

Krefeld, , Germany

Site Status

Office of Peter Anhut

Kronach, , Germany

Site Status

Office of Albrecht Kretzschmar

Leipzig, , Germany

Site Status

Office of Nidal Gazawi

Leipzig, , Germany

Site Status

Office of Udo Hieber

Mannheim, , Germany

Site Status

Office of Christoph Salat

München, , Germany

Site Status

Office of Christian Lerchenmüller

Münster, , Germany

Site Status

Office of Burkhard Otremba

Oldenburg, , Germany

Site Status

Office of Julian Topaly

Osnabrück, , Germany

Site Status

Office of Andre-Robert Rotmann

Rodgau, , Germany

Site Status

Office of Rene Schubert

Scheibenberg, , Germany

Site Status

Office of Matthias Groschek

Stolberg, , Germany

Site Status

Office of Carsten Hielscher

Stralsund, , Germany

Site Status

Office of Thomas Kuhn

Stuttgart, , Germany

Site Status

Office of Ortwin Klein

Wiesbaden, , Germany

Site Status

Countries

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Germany

References

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Otremba B, Hielscher C, Petersen V, Petrik C. Home administration of filgrastim (Nivestim) in primary prophylaxis of chemotherapy-induced febrile neutropenia. Patient Prefer Adherence. 2018 Oct 16;12:2179-2186. doi: 10.2147/PPA.S168029. eCollection 2018.

Reference Type DERIVED
PMID: 30410313 (View on PubMed)

Other Identifiers

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C1121004

Identifier Type: OTHER

Identifier Source: secondary_id

ZOB-NIV-1504

Identifier Type: -

Identifier Source: org_study_id

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