Vascular Inflammation and Cholesterol Lowering Therapy

NCT ID: NCT02941016

Last Updated: 2020-10-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

WITHDRAWN

Clinical Phase

PHASE4

Study Classification

INTERVENTIONAL

Study Start Date

2016-10-31

Study Completion Date

2020-10-01

Brief Summary

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This study aim to detect change in vascular inflammation following intense lipid lowering therapy

Detailed Description

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Conditions

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Lipid Lowering, Vascular Inflammation

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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Lipid lowering

Group Type EXPERIMENTAL

Evolocumab or Alirocumab

Intervention Type DRUG

All patients are treated with PCSK-9 inhibitors (Evolocumab or Alirocumab) to lower cholesterol

Interventions

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Evolocumab or Alirocumab

All patients are treated with PCSK-9 inhibitors (Evolocumab or Alirocumab) to lower cholesterol

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* treatment with PCSK-9 inhibitors

Exclusion Criteria

* Infection Pregnancy Severe claustrophobia Weight \>140 kg
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Rigshospitalet, Denmark

OTHER

Sponsor Role lead

Responsible Party

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Rasmus S. Ripa

Staff Physician

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Rasmus S Ripa, MD, DMSc

Role: PRINCIPAL_INVESTIGATOR

Rigshospitalet, Denmark

Locations

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Rigshospitalet

Copenhagen, , Denmark

Site Status

Countries

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Denmark

Other Identifiers

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0002

Identifier Type: -

Identifier Source: org_study_id

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