Evaluation of Drug Utilization Patterns for Extended Release/Long Acting Opioids and Comparator Products

NCT ID: NCT02925806

Last Updated: 2016-10-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

5575834 participants

Study Classification

OBSERVATIONAL

Brief Summary

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A drug utilization study will be performed to describe trends in the number of prescriptions and patients for class REMS ER/LA opioids and comparator products.

Detailed Description

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A drug utilization study will be performed to describe trends in the number of prescriptions and patients for class REMS ER/LA opioids and comparator products.

The specific objectives of the Drug Utilization Study are:

1. To estimate trends by month in the number of prescriptions for a one-year period before, and each month after, the implementation of the REMS
2. To compare average number of prescriptions per 3 month (quarter) period in the 2 years before as compared to the same measure during Implementation and the Active Period
3. To evaluate change by patient characteristics (age group, gender, pay type, prescriber specialty)
4. To compare the trends in prescribing, both number of prescriptions and patients, by prescriber specialty

These trends and changes over time will be estimated for the following groups of opioids:
* ER/LA opioids included in the class REMS
* Comparator products/classes

* Immediate release (IR) opioids
* Celecoxib
* Benzodiazepines
5. To show switches (absolute and rates of switching) from ER/LA opioids to comparator analgesics (IR opioids or celecoxib) with introduction of REMS

Conditions

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Opioid Related Disorders Opiate Addiction Narcotic Abuse Drug Abuse

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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ER/LA opioids included in the class REMS

Non-interventional study - retrospective database review

Intervention Type OTHER

IR Opioids

Non-interventional study - retrospective database review

Intervention Type OTHER

Celecoxib

Non-interventional study - retrospective database review

Intervention Type OTHER

Benzodiazepines

Non-interventional study - retrospective database review

Intervention Type OTHER

Interventions

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Non-interventional study - retrospective database review

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Subjects filling a prescription for a product of interest during the specified time period will be included.

Exclusion Criteria

* None
Maximum Eligible Age

100 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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ER/LA Opioid REMS Program Companies (RPC)

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Other Identifiers

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Assessment 6

Identifier Type: -

Identifier Source: org_study_id

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