Trial Outcomes & Findings for Mechanisms for Alcohol Treatment Change [MATCH] Study (NCT NCT02918565)

Last Updated: 2023-12-05

Results Overview

Measured by the # days on the Timeline Followback Calendar that a male reported 5+ drinks or a female reported 4+ drinks

Recruitment status

COMPLETED

Study phase

Target enrollment

1131 participants

Primary outcome timeframe

12 weeks after starting intervention

Results posted on

2023-12-05

Participant Flow

Participant milestones

Participant milestones
Measure	COMBO 12 weeks of interactive text messaging incorporating features of DCF, ARF and AGS. COMBO: 12 weeks of interactive text messaging incorporating features of DCF, ARF and AGS.	Adaptive Goal Support (AGS) 12 weeks of interactive text messaging focused on providing adaptive goal support (based on running average of max drinks consumed). Adaptive Goal Support (AGS): 12 weeks of interactive text messaging focused on providing adaptive goal support (based on running average of max drinks consumed).	Alcohol Risk Feedback (ARF) 12 weeks of interactive text messaging focused on providing feedback related only to post-weekend alcohol consumption (max drinks consumed on any occasion over the weekend). Alcohol Risk Feedback (ARF): 12 weeks of interactive text messaging focused on providing feedback related only to post-weekend alcohol consumption (max drinks consumed on any occasion over the weekend).	Drinking Cognition Feedback (DCF) 12 weeks of interactive text messaging focused on providing feedback related only to pre-weekend drinking cognitions (plans, desire to get drunk). Drinking Cognition Feedback (DCF): 12 weeks of interactive text messaging focused on providing feedback related only to pre-weekend drinking cognitions (plans, desire to get drunk).	Control 12 weeks of text message assessments without any feedback
Overall Study STARTED	220	213	232	224	242
Overall Study COMPLETED	213	202	221	216	231
Overall Study NOT COMPLETED	7	11	11	8	11

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Mechanisms for Alcohol Treatment Change [MATCH] Study

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure	COMBO n=220 Participants 12 weeks of interactive text messaging incorporating features of DCF, ARF and AGS. COMBO: 12 weeks of interactive text messaging incorporating features of DCF, ARF and AGS.	Adaptive Goal Support (AGS) n=213 Participants 12 weeks of interactive text messaging focused on providing adaptive goal support (based on running average of max drinks consumed). Adaptive Goal Support (AGS): 12 weeks of interactive text messaging focused on providing adaptive goal support (based on running average of max drinks consumed).	Alcohol Risk Feedback (ARF) n=232 Participants 12 weeks of interactive text messaging focused on providing feedback related only to post-weekend alcohol consumption (max drinks consumed on any occasion over the weekend). Alcohol Risk Feedback (ARF): 12 weeks of interactive text messaging focused on providing feedback related only to post-weekend alcohol consumption (max drinks consumed on any occasion over the weekend).	Drinking Cognition Feedback (DCF) n=224 Participants 12 weeks of interactive text messaging focused on providing feedback related only to pre-weekend drinking cognitions (plans, desire to get drunk). Drinking Cognition Feedback (DCF): 12 weeks of interactive text messaging focused on providing feedback related only to pre-weekend drinking cognitions (plans, desire to get drunk).	Control n=242 Participants 12 weeks of text message assessments without any feedback	Total n=1131 Participants Total of all reporting groups
Age, Continuous	21.8 years STANDARD_DEVIATION 2.2 • n=5 Participants	22.2 years STANDARD_DEVIATION 2.0 • n=7 Participants	22.1 years STANDARD_DEVIATION 2.1 • n=5 Participants	22.3 years STANDARD_DEVIATION 2.1 • n=4 Participants	22.1 years STANDARD_DEVIATION 2.0 • n=21 Participants	22.1 years STANDARD_DEVIATION 2.1 • n=10 Participants
Sex: Female, Male Female	145 Participants n=5 Participants	143 Participants n=7 Participants	163 Participants n=5 Participants	156 Participants n=4 Participants	168 Participants n=21 Participants	775 Participants n=10 Participants
Sex: Female, Male Male	75 Participants n=5 Participants	70 Participants n=7 Participants	69 Participants n=5 Participants	68 Participants n=4 Participants	74 Participants n=21 Participants	356 Participants n=10 Participants
Ethnicity (NIH/OMB) Hispanic or Latino	19 Participants n=5 Participants	19 Participants n=7 Participants	17 Participants n=5 Participants	14 Participants n=4 Participants	28 Participants n=21 Participants	97 Participants n=10 Participants
Ethnicity (NIH/OMB) Not Hispanic or Latino	201 Participants n=5 Participants	194 Participants n=7 Participants	215 Participants n=5 Participants	210 Participants n=4 Participants	214 Participants n=21 Participants	1034 Participants n=10 Participants
Ethnicity (NIH/OMB) Unknown or Not Reported	0 Participants n=5 Participants	0 Participants n=7 Participants	0 Participants n=5 Participants	0 Participants n=4 Participants	0 Participants n=21 Participants	0 Participants n=10 Participants
Race (NIH/OMB) American Indian or Alaska Native	0 Participants n=5 Participants	0 Participants n=7 Participants	0 Participants n=5 Participants	0 Participants n=4 Participants	0 Participants n=21 Participants	0 Participants n=10 Participants
Race (NIH/OMB) Asian	6 Participants n=5 Participants	1 Participants n=7 Participants	3 Participants n=5 Participants	0 Participants n=4 Participants	0 Participants n=21 Participants	10 Participants n=10 Participants
Race (NIH/OMB) Native Hawaiian or Other Pacific Islander	0 Participants n=5 Participants	0 Participants n=7 Participants	0 Participants n=5 Participants	0 Participants n=4 Participants	0 Participants n=21 Participants	0 Participants n=10 Participants
Race (NIH/OMB) Black or African American	76 Participants n=5 Participants	81 Participants n=7 Participants	82 Participants n=5 Participants	86 Participants n=4 Participants	95 Participants n=21 Participants	420 Participants n=10 Participants
Race (NIH/OMB) White	116 Participants n=5 Participants	112 Participants n=7 Participants	132 Participants n=5 Participants	123 Participants n=4 Participants	126 Participants n=21 Participants	609 Participants n=10 Participants
Race (NIH/OMB) More than one race	13 Participants n=5 Participants	14 Participants n=7 Participants	11 Participants n=5 Participants	9 Participants n=4 Participants	14 Participants n=21 Participants	61 Participants n=10 Participants
Race (NIH/OMB) Unknown or Not Reported	9 Participants n=5 Participants	5 Participants n=7 Participants	4 Participants n=5 Participants	6 Participants n=4 Participants	7 Participants n=21 Participants	31 Participants n=10 Participants
Any tobacco use	123 participants n=5 Participants	117 participants n=7 Participants	120 participants n=5 Participants	117 participants n=4 Participants	105 participants n=21 Participants	582 participants n=10 Participants
Impulsivity score	41.4 units on a scale STANDARD_DEVIATION 7.4 • n=5 Participants	41.9 units on a scale STANDARD_DEVIATION 6.7 • n=7 Participants	41.3 units on a scale STANDARD_DEVIATION 6.9 • n=5 Participants	41.3 units on a scale STANDARD_DEVIATION 6.9 • n=4 Participants	41.4 units on a scale STANDARD_DEVIATION 7.7 • n=21 Participants	41.5 units on a scale STANDARD_DEVIATION 7.1 • n=10 Participants

PRIMARY outcome

Timeframe: 12 weeks after starting intervention

Population: CCA

Measured by the # days on the Timeline Followback Calendar that a male reported 5+ drinks or a female reported 4+ drinks

Outcome measures

Outcome measures
Measure	COMBO n=169 Participants 12 weeks of interactive text messaging incorporating features of DCF, ARF and AGS. COMBO: 12 weeks of interactive text messaging incorporating features of DCF, ARF and AGS.	Adaptive Goal Support (AGS) n=175 Participants 10 weeks of interactive text messaging focused on providing adaptive goal support (based on running average of max drinks consumed). Adaptive Goal Support (AGS): 12 weeks of interactive text messaging focused on providing adaptive goal support (based on running average of max drinks consumed).	Alcohol Risk Feedback (ARF) n=192 Participants 12 weeks of interactive text messaging focused on providing feedback related only to post-weekend alcohol consumption (max drinks consumed on any occasion over the weekend). Alcohol Risk Feedback (ARF): 12 weeks of interactive text messaging focused on providing feedback related only to post-weekend alcohol consumption (max drinks consumed on any occasion over the weekend).	Drinking Cognition Feedback (DCF) n=180 Participants 12 weeks of interactive text messaging focused on providing feedback related only to pre-weekend drinking cognitions (plans, desire to get drunk). Drinking Cognition Feedback (DCF): 12 weeks of interactive text messaging focused on providing feedback related only to pre-weekend drinking cognitions (plans, desire to get drunk).	Control n=201 Participants 12 weeks of text message assessments without any feedback
Number of Binge Drinking Days	2.3 days Standard Deviation 3.3	2.6 days Standard Deviation 4.2	2.9 days Standard Deviation 4.3	3.0 days Standard Deviation 4.3	3.4 days Standard Deviation 4.2

SECONDARY outcome

Timeframe: 12 weeks after starting intervention

drinks per drinking day = mean drinks divided by the number of days with any alcohol consumption using the 30-day TLFB Calendar.

Outcome measures

Outcome measures
Measure	COMBO n=169 Participants 12 weeks of interactive text messaging incorporating features of DCF, ARF and AGS. COMBO: 12 weeks of interactive text messaging incorporating features of DCF, ARF and AGS.	Adaptive Goal Support (AGS) n=175 Participants 10 weeks of interactive text messaging focused on providing adaptive goal support (based on running average of max drinks consumed). Adaptive Goal Support (AGS): 12 weeks of interactive text messaging focused on providing adaptive goal support (based on running average of max drinks consumed).	Alcohol Risk Feedback (ARF) n=192 Participants 12 weeks of interactive text messaging focused on providing feedback related only to post-weekend alcohol consumption (max drinks consumed on any occasion over the weekend). Alcohol Risk Feedback (ARF): 12 weeks of interactive text messaging focused on providing feedback related only to post-weekend alcohol consumption (max drinks consumed on any occasion over the weekend).	Drinking Cognition Feedback (DCF) n=180 Participants 12 weeks of interactive text messaging focused on providing feedback related only to pre-weekend drinking cognitions (plans, desire to get drunk). Drinking Cognition Feedback (DCF): 12 weeks of interactive text messaging focused on providing feedback related only to pre-weekend drinking cognitions (plans, desire to get drunk).	Control n=201 Participants 12 weeks of text message assessments without any feedback
Drinks Per Drinking Day	2.9 drinks/day Standard Deviation 2.5	2.9 drinks/day Standard Deviation 2.0	3.2 drinks/day Standard Deviation 2.1	3.0 drinks/day Standard Deviation 2.2	3.5 drinks/day Standard Deviation 2.2

SECONDARY outcome

Timeframe: 12 weeks after starting intervention

Using the Timeline Followback Calendar, any male participant reported one or more days with 5+ drinks or a female with one or more days with 4+ drinks are coded=1; otherwise participant is coded=0

Outcome measures

Outcome measures
Measure	COMBO n=169 Participants 12 weeks of interactive text messaging incorporating features of DCF, ARF and AGS. COMBO: 12 weeks of interactive text messaging incorporating features of DCF, ARF and AGS.	Adaptive Goal Support (AGS) n=175 Participants 10 weeks of interactive text messaging focused on providing adaptive goal support (based on running average of max drinks consumed). Adaptive Goal Support (AGS): 12 weeks of interactive text messaging focused on providing adaptive goal support (based on running average of max drinks consumed).	Alcohol Risk Feedback (ARF) n=192 Participants 12 weeks of interactive text messaging focused on providing feedback related only to post-weekend alcohol consumption (max drinks consumed on any occasion over the weekend). Alcohol Risk Feedback (ARF): 12 weeks of interactive text messaging focused on providing feedback related only to post-weekend alcohol consumption (max drinks consumed on any occasion over the weekend).	Drinking Cognition Feedback (DCF) n=180 Participants 12 weeks of interactive text messaging focused on providing feedback related only to pre-weekend drinking cognitions (plans, desire to get drunk). Drinking Cognition Feedback (DCF): 12 weeks of interactive text messaging focused on providing feedback related only to pre-weekend drinking cognitions (plans, desire to get drunk).	Control n=201 Participants 12 weeks of text message assessments without any feedback
Count of Participants With Any Binge Drinking Day	95 Participants	110 Participants	119 Participants	115 Participants	144 Participants

SECONDARY outcome

Timeframe: 12 weeks after starting intervention

Brief Young Adult Alcohol Consequences Questionnaire (B-YAACQ). The B-YAACQ is a 24-item measure of alcohol- related problems that utilizes a dichotomous (present or absent) scoring format. Sum of items 1-48. Higher scores (count of items marked as 'present') on the B-YAACQ not only indicate a wider variety but also reflect a more severe pattern of alcohol-related problems.