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Mechanisms for Alcohol Treatment Change [MATCH] Study

NCT ID: NCT02918565

Last Updated: 2023-12-05

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

1131 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-12-31

Study Completion Date

2021-11-22

Brief Summary

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A 5-arm randomized trial to determine what components of a text message intervention are necessary to reduce hazardous drinking among young adults and mechanisms through which these changes occur.

Detailed Description

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Young adults ages 18-25 have high rates of hazardous alcohol use and alcohol-related consequences. The Emergency Department (ED) provides an important opportunity to identify young adult hazardous drinkers who could benefit from interventions. A Text Message (TM) intervention was shown to reduce alcohol consumption among young adult ED patients, showing durable effects over 9-months. The TM intervention uses behavior change techniques with the largest effect sizes in an alcohol intervention meta-analysis: "goal commitment" and "self-monitoring", along with real-time "feedback". However, the unique effect of these ingredients, and mechanisms (processes occurring within the individual) through which they operate to reduce drinking remain unclear, a critical gap addressed by this project. Young adult ED patients (ages 18-25) who screen positive for hazardous drinking will be recruited to participate in a randomized trial to determine how best to help individuals reduce hazardous drinking. All participants will be asked to complete web-based surveys at baseline, 12 and 24 weeks after enrollment, complete brief psychomotor tasks weekly for 14 weeks, and respond to text messages each Thursday and Sunday for the next 12 weeks. Those randomized to the TM interventions will additionally receive feedback on their text reports. The four TM intervention arms are: (1) Drinking Cognition Feedback (DCF), (2) Alcohol Risk Feedback (ARF), (3) Adaptive Goal Support (AGS) and (4) a combination of DCF, ARF, and AGS=COMBO). Study results have implications for designing efficient mobile interventions, and developing a dynamic theory of behavior change.

Conditions

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Alcohol Consumption

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

DOUBLE

Investigators Outcome Assessors

Study Groups

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Drinking Cognition Feedback (DCF)

12 weeks of interactive text messaging focused on providing feedback related only to pre-weekend drinking cognitions (plans, desire to get drunk).

Group Type EXPERIMENTAL

Drinking Cognition Feedback (DCF)

Intervention Type BEHAVIORAL

12 weeks of interactive text messaging focused on providing feedback related only to pre-weekend drinking cognitions (plans, desire to get drunk).

Alcohol Risk Feedback (ARF)

12 weeks of interactive text messaging focused on providing feedback related only to post-weekend alcohol consumption (max drinks consumed on any occasion over the weekend).

Group Type EXPERIMENTAL

Alcohol Risk Feedback (ARF)

Intervention Type BEHAVIORAL

12 weeks of interactive text messaging focused on providing feedback related only to post-weekend alcohol consumption (max drinks consumed on any occasion over the weekend).

Adaptive Goal Support (AGS)

10 weeks of interactive text messaging focused on providing adaptive goal support (based on running average of max drinks consumed).

Group Type EXPERIMENTAL

Adaptive Goal Support (AGS)

Intervention Type BEHAVIORAL

12 weeks of interactive text messaging focused on providing adaptive goal support (based on running average of max drinks consumed).

COMBO

12 weeks of interactive text messaging incorporating features of DCF, ARF and AGS.

Group Type EXPERIMENTAL

COMBO

Intervention Type BEHAVIORAL

12 weeks of interactive text messaging incorporating features of DCF, ARF and AGS.

Control

12 weeks of text message assessments without any feedback

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Drinking Cognition Feedback (DCF)

12 weeks of interactive text messaging focused on providing feedback related only to pre-weekend drinking cognitions (plans, desire to get drunk).

Intervention Type BEHAVIORAL

Alcohol Risk Feedback (ARF)

12 weeks of interactive text messaging focused on providing feedback related only to post-weekend alcohol consumption (max drinks consumed on any occasion over the weekend).

Intervention Type BEHAVIORAL

Adaptive Goal Support (AGS)

12 weeks of interactive text messaging focused on providing adaptive goal support (based on running average of max drinks consumed).

Intervention Type BEHAVIORAL

COMBO

12 weeks of interactive text messaging incorporating features of DCF, ARF and AGS.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* total score of \>2 for women or \>3 for men on the AUDIT-C
* at least 1 binged drinking episode in the prior 30 days

Exclusion Criteria

* no cell phone with text messaging
* have been diagnosed with an alcohol or substance use disorder
* pregnant or planning pregnancy
* taking medicine for a psychiatric disorder (including depression, anxiety)
* taking any medicine that could interact with alcohol
Minimum Eligible Age

18 Years

Maximum Eligible Age

25 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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National Institute on Alcohol Abuse and Alcoholism (NIAAA)

NIH

Sponsor Role collaborator

University of Pittsburgh

OTHER

Sponsor Role lead

Responsible Party

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Maria Pacella

Research Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Brian Suffoletto, MD MS

Role: PRINCIPAL_INVESTIGATOR

University of Pittsburgh

Locations

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University of Pittsburgh Medical Center Emergency Department

Pittsburgh, Pennsylvania, United States

Site Status

Countries

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United States

References

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Chung T, Suffoletto B, Bhurosy T. Which intervention works for whom: Identifying pre-treatment characteristics that predict who will benefit from a specific alcohol text message intervention from a randomized trial. J Subst Use Addict Treat. 2025 Jan;168:209562. doi: 10.1016/j.josat.2024.209562. Epub 2024 Nov 4.

Reference Type DERIVED
PMID: 39505110 (View on PubMed)

Bae SW, Suffoletto B, Zhang T, Chung T, Ozolcer M, Islam MR, Dey AK. Leveraging Mobile Phone Sensors, Machine Learning, and Explainable Artificial Intelligence to Predict Imminent Same-Day Binge-drinking Events to Support Just-in-time Adaptive Interventions: Algorithm Development and Validation Study. JMIR Form Res. 2023 May 4;7:e39862. doi: 10.2196/39862.

Reference Type DERIVED
PMID: 36809294 (View on PubMed)

Suffoletto B, Field M, Chung T. Attentional and approach biases to alcohol cues among young adult drinkers: An ecological momentary assessment study. Exp Clin Psychopharmacol. 2020 Dec;28(6):649-658. doi: 10.1037/pha0000343. Epub 2019 Dec 30.

Reference Type DERIVED
PMID: 31886700 (View on PubMed)

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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R01AA023650

Identifier Type: NIH

Identifier Source: secondary_id

View Link

STUDY19050262

Identifier Type: -

Identifier Source: org_study_id