Predictors of De-novo Development of Obstructive Sleep Apnea in Pregnancy
NCT ID: NCT02917876
Last Updated: 2024-11-22
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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ACTIVE_NOT_RECRUITING
450 participants
OBSERVATIONAL
2016-11-30
2025-05-01
Brief Summary
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Detailed Description
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1. measurements of body composition
2. anthropometric measures
3. sleep and mood questionnaires
4. Home sleep studies
5. blood testing for biological markers
6. salivary testing for hormonal markers
7. pulmonary function tests and upper airway patency measurements
Women without sleep apnea at enrollment will then be followed longitudinally for the development of obstructive sleep apnea during pregnancy with repeat assessment during their third trimester. Women diagnosed with sleep apnea at enrollment will have no further assessment in late pregnancy.
Monetary incentives will also be issued at data collection points. Subjects will receive small gift incentives such as baby-related items.
Conditions
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Study Design
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COHORT
PROSPECTIVE
Eligibility Criteria
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Inclusion Criteria
* BMI \>30 kg/m2 at recruitment
* \>18 years of age
* Ability to give informed consent
* Twin pregnancies
18 Years
FEMALE
No
Sponsors
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Brown University
OTHER
Rhode Island Hospital
OTHER
Women and Infants Hospital of Rhode Island
OTHER
The Miriam Hospital
OTHER
Responsible Party
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Ghada Bourjeily
Associate Professor of Medicine
Principal Investigators
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Ghada Bourjeily, MD
Role: PRINCIPAL_INVESTIGATOR
The Miriam Hospital
Locations
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The Miriam Hospital
Providence, Rhode Island, United States
Countries
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References
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Bublitz MH, Nillni Y, Nugent NR, Sanapo L, Habr N, Bourjeily G. Posttraumatic stress disorder, diurnal cortisol, and ambulatory blood pressure in early and late pregnancy. J Trauma Stress. 2023 Feb;36(1):239-246. doi: 10.1002/jts.22895. Epub 2022 Dec 4.
Sanapo L, Bublitz MH, Bai A, Mehta N, Messerlian GM, Catalano P, Bourjeily G. Association between sleep disordered breathing in early pregnancy and glucose metabolism. Sleep. 2022 Apr 11;45(4):zsab281. doi: 10.1093/sleep/zsab281.
Other Identifiers
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