EC-MOTION : ExtraCorporeal Membrane Oxygenation and Therapeutic Drug Monitoring of Drugs of infectION

NCT ID: NCT02917486

Last Updated: 2016-12-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

60 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-01-31

Study Completion Date

2019-07-31

Brief Summary

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The objective of the study is to investigate the exposure difference between antibiotic studied patients in intensive care with Extracorporeal Membrane Oxygenation and patients without Extracorporeal Membrane Oxygenation.

The exhibition is evaluated by population pharmacokinetic modeling.

Detailed Description

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Conditions

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Infection

Keywords

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ExtraCorporeal Membrane Oxygenation patient in intensive care pharmacokinetic modeling

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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ECMO piperacillin

patients in intensive care treated with ECMO with antiinfective therapy : piperacillin

blood sample

Intervention Type OTHER

without ECMO piperacillin

patients in intensive care without ECMO with antiinfective therapy : piperacillin

blood sample

Intervention Type OTHER

Interventions

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blood sample

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Age over 18 years
* Hospitalisation in intensive care
* Treatment with ECMO or without ECMO
* Introducing sepsis treated with an anti-infective molecule studied (piperacillin) for less than 48 hours
* With an arterial catheter
* Patient Information or their next of kin according to the patients status.

Exclusion Criteria

* Pregnancy
* Major person under legal protection (backup justice, trusteeship, quardianship), person deprived of liberty
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Rennes University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Pierre Fillatre

Role: PRINCIPAL_INVESTIGATOR

CHU Rennes

Locations

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CHU Rennes

Rennes, , France

Site Status RECRUITING

Countries

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France

Central Contacts

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Pierre Fillatre

Role: CONTACT

Email: [email protected]

Anne Ganivet

Role: CONTACT

Email: [email protected]

Facility Contacts

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Pierre Fillatre

Role: primary

Other Identifiers

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35RC15_8901

Identifier Type: -

Identifier Source: org_study_id