Shifting Salty Taste Preferences in Children

NCT ID: NCT02909764

Last Updated: 2019-09-30

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

39 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-01-31

Study Completion Date

2016-12-31

Brief Summary

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The goals of the proposed research are to determine whether repeated exposure to a low sodium food will result in reduced preference for salt in that food among children; and to determine whether such reductions in preference are related to dietary intake of salt, taste receptor genotype, and anthropometric and physiological measures.

Detailed Description

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This is a within- and between-subjects randomized controlled trial on children consuming either a low sodium or a higher sodium cereal over a 2-month period to determine if repeated exposure to the low sodium cereal is effective for reducing preference for salt in that food. Children will be genotyped for markers related to taste, dietary intake will be recorded, and anthropometric and physiological measures will be collected at baseline.

Conditions

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Development

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

TRIPLE

Participants Caregivers Outcome Assessors

Study Groups

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Control Group

Children will receive regularly salted cereal to consume 4 times per week over a 2-month period.

Group Type NO_INTERVENTION

No interventions assigned to this group

Low Sodium Group

Intervention: Children will receive low sodium cereal to consume 4 times per week over a 2-month period.

Group Type EXPERIMENTAL

Low Sodium Group

Intervention Type OTHER

Breakfast Cereal

Interventions

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Low Sodium Group

Breakfast Cereal

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Healthy
* Willingness to consume no other cereals during intervention

Exclusion Criteria

* Allergies and/or taking medication that affects taste
Minimum Eligible Age

7 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Monell Chemical Senses Center

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Julie A Mennella, PhD

Role: PRINCIPAL_INVESTIGATOR

Monell Chemical Senses Center

Locations

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Monell Chemical Senses Center

Philadelphia, Pennsylvania, United States

Site Status

Countries

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United States

References

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Bobowski N, Mennella JA. Repeated Exposure to Low-Sodium Cereal Affects Acceptance but Does not Shift Taste Preferences or Detection Thresholds of Children in a Randomized Clinical Trial. J Nutr. 2019 May 1;149(5):870-876. doi: 10.1093/jn/nxz014.

Reference Type DERIVED
PMID: 31006818 (View on PubMed)

Other Identifiers

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823281

Identifier Type: -

Identifier Source: org_study_id

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