Clinical Database Associated With a Biological Banking Accessible to Initiate Epidemiological and Translational Collaborative Researches in Kidney Transplantation

NCT ID: NCT02900040

Last Updated: 2016-09-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

30000 participants

Study Classification

OBSERVATIONAL

Study Start Date

1994-01-31

Study Completion Date

2050-01-31

Brief Summary

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The French DIVAT (standing for Données Informatisées et VAlidées en Transplantation in french, and in English "Computerized and VAlidated Data in Transplantation" ) cohort was Kicked off in 1994 by the Transplantation Urology Nephrology Institute of the Nantes University Hospital in France. The primary objective of this multicenter computerized database was to enable prospective clinical and epidemiological research studies concerning kidney transplant recipients, particularly focusing on mid- and long-term clinical outcomes, therapeutic strategies and public health issues. The patient-case system of the DIVAT cohort allows the monitoring of medical records of all patient-specific and allograft-specific data, including bio-banking since 2005. Data are collected from the date of transplantation until the graft failure, at each scheduled outpatient visit or hospital admission motivating by a new clinical, therapeutical or biological expression. The DIVAT cohort contains information on more than 11000 transplant recipients between 1994 and today, issued from 8 French university hospitals centers (the DIVAT Network is organized by a consortium agreement). 18% of all patients underwent retransplantation and 11% of all kidney transplants originated from living donors. The DIVAT network heavily works to ensure a high-quality data collection with the aim of exploring adequately the complex post-transplantation process. The Divat network encourage collaborations and enables interested researchers to submit a research project by completing a request form available on the DIVAT website (http://www.divat.fr/en) describing the context, objectives and design of the study

Detailed Description

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Conditions

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Kidney Transplantation

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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patients with kidney transplantations

patients with kidney transplantations

kidney transplantation

Intervention Type OTHER

Interventions

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kidney transplantation

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* over the age of 18 years
* with renal transplant

Exclusion Criteria

* minor
* pediatric transplantation
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Nantes University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Magali Giral, PU-PH

Role: PRINCIPAL_INVESTIGATOR

Nantes Universuty Hospital

Locations

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Docteur Buron

Lyon, , France

Site Status RECRUITING

Professeur Mourad

Montpellier, , France

Site Status RECRUITING

Professeur Kessler

Nancy, , France

Site Status RECRUITING

Professeur Ladriere

Nancy, , France

Site Status RECRUITING

Pr Cassuto

Nice, , France

Site Status RECRUITING

Professeur Kreis

Paris, , France

Site Status RECRUITING

Professeur Legendre

Paris, , France

Site Status RECRUITING

Professeur Rostaing

Toulouse, , France

Site Status RECRUITING

Countries

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France

Central Contacts

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Magali Giral, PU-PH

Role: CONTACT

+33 (0)2 40 08 74 43

References

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Danger R, Le Berre L, Cadoux M, Kerleau C, Papuchon E, Mai HL, Nguyen TV, Guerif P, Morelon E, Thaunat O, Legendre C, Anglicheau D, Lefaucheur C, Couzi L, Del Bello A, Kamar N, Le Quintrec M, Goutaudier V, Renaudin K, Giral M, Brouard S; DIVAT Consortium. Subclinical rejection-free diagnostic after kidney transplantation using blood gene expression. Kidney Int. 2023 Jun;103(6):1167-1179. doi: 10.1016/j.kint.2023.03.019. Epub 2023 Mar 27.

Reference Type DERIVED
PMID: 36990211 (View on PubMed)

Other Identifiers

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RC12_0452

Identifier Type: -

Identifier Source: org_study_id

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