Changes in the Diameter of Retinal Vessels After Remote Ischemic Conditioning

NCT ID: NCT02898480

Last Updated: 2019-04-05

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 20 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2016-09-30
• Study Completion Date: 2017-05-31

Brief Summary

Remote ischemic conditioning (RIC) is a therapeutic strategy for protecting organs or tissue against the detrimental effects of acute ischemia-reperfusion injury. It remains unknown whether this can be used in retinal vascular occlusive diseases. The purpose of the present study is to examine whether the autoregulation of retinal vessel diameters in normal persons change after remote ischemic conditioning.

Conditions

Retinal Artery Occlusion; Retinal Vein Occlusion

Study Design

• Allocation Method: NA
• Intervention Model: SINGLE_GROUP
• Primary Study Purpose: BASIC_SCIENCE
• Blinding Strategy: NONE

Study Groups

Remote ischemic conditioning

Group Type: EXPERIMENTAL

Remote ischemic conditioning

Intervention Type: PROCEDURE

Briefly reversible restricting of blood flow to upper limb in four cycles of 5 minutes of inflation at 200mm Hg followed by 5 minutes of deflation.

Interventions

Remote ischemic conditioning

Briefly reversible restricting of blood flow to upper limb in four cycles of 5 minutes of inflation at 200mm Hg followed by 5 minutes of deflation.

Intervention Type: PROCEDURE

Eligibility Criteria

Inclusion Criteria

• Normal persons

Exclusion Criteria

• Present or previous eye disease
• Use of medications except anti-conceptive
• Epilepsy
• Pregnancy or lactation

• Minimum Eligible Age: 20 Years
• Maximum Eligible Age: 35 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

University of Aarhus

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Other Identifiers

RIK-DVA

Identifier Type: -

Identifier Source: org_study_id