Predictive Value of Dynamic Combination of BNP and NGAL for the Prognosis of Patients With Sepsis

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

124 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-06-30

Study Completion Date

2016-02-29

Brief Summary

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Objective: to clarify the predictive value of brain natriuretic peptide (BNP) in combination with neutrophil gelatinase associated lipocalin (NGAL) for the prognosis of patients with sepsis.

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Detailed Description

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Conditions

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28-day Mortality Sepsis

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

FACTORIAL

Primary Study Purpose

SCREENING

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BNP and NGAL

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* age ≥18 years and \<85 years;
* presence of severe sepsis according to Survival Sepsis Campaign 10;
* all patients voluntarily joined this study with informed consents.

Exclusion Criteria

* participated in other trials within 30 days before the criteria for this trial were met;
* expected to die within 24 hours;
* pregnant;
* advanced malignancy with life expectancy \<6 months;
* history of congestive heart failure;
* chronic renal dysfunction (baseline creatinine \>176.8μmol/L); and
* relatives were unwilling to agree to the use of full life support.

Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No