Anterior Segment Imaging With Ultrahigh-resolution OCT in Patients With Glaucoma and PEX - a Pilot Study
NCT ID: NCT02865473
Last Updated: 2022-04-07
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
90 participants
INTERVENTIONAL
2016-04-20
2023-12-31
Brief Summary
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The aim of the study is to develop a measurement protocol for OCT imaging and characterization of the anterior chamber in glaucoma patients.
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Detailed Description
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Conditions
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Study Design
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NON_RANDOMIZED
PARALLEL
BASIC_SCIENCE
NONE
Study Groups
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primary open angle glaucoma patients
No interventions assigned to this group
patients with primary angle closure
No interventions assigned to this group
patients with neovascular glaucoma
No interventions assigned to this group
PEX glaucoma patients
No interventions assigned to this group
glaucoma patients with filtering bleb
No interventions assigned to this group
healthy volunteers
instillation of antiglaucoma treatment in the study eye
Pilocarpine
topical instillation into the study eye
Interventions
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Pilocarpine
topical instillation into the study eye
Eligibility Criteria
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Inclusion Criteria
For patients with primary open angle glaucoma:
* Diagnosed primary open angle glaucoma
* Visual field defects and optic nerve head appearance characteristic for glaucoma
* Open anterior chamber angle as evidenced by gonioscopy
* No previous glaucoma surgery
* No previous cataract surgery
For patients with primary angle closure:
* Angle closure predisposition as evidenced from goniosocopy
* No previous glaucoma surgery
For patients with neovascular glaucoma:
\- Neovascularization in the anterior chamber angle
For patients with pseudoexfolation deposits on the lens:
* PEX glaucoma as evidenced from slit lamp examination
* Visual field defects and optic nerve head appearance characteristic for glaucoma
* Open anterior chamber angle as evidenced by gonioscopy
* No previous glaucoma or cataract surgery
For glaucoma patients with filtering bleb after trabeculectomy:
* Patients with history of trabeculectomy secondary to open angle glaucoma in the previous three months
* No cataract surgery
For healthy volunteers:
* No evidence of ocular disease
* No degenerative changes in the retina in funduscopy after mydriasis
* Ametropia less than 3 dpt.
Exclusion Criteria
* Pregnancy, planned pregnancy or lactating
* Ocular inflammation and ocular disease interfering with the study aims as judged by the investigator
18 Years
ALL
Yes
Sponsors
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Medical University of Vienna
OTHER
Responsible Party
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Gerhard Garhofer
Assoc. Prof. PD Dr.
Locations
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Department of Clinical Pharmacology, Medical University of Vienna
Vienna, , Austria
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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OPHT-010915
Identifier Type: -
Identifier Source: org_study_id
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