Inflammatory Response as a Prognostic Factor of Recurrence of Atrial Fibrillation After Ablation

NCT ID: NCT02844959

Last Updated: 2016-07-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

120 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-07-31

Study Completion Date

2018-07-31

Brief Summary

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The aim of this study is to evaluate inflammatory response as a prognostic factor of atrial fibrillation recurrency after ablation. Inflammatory response will be assessed by double measurement of C-reactive protein, fibroblast growth factor 2 (FGF2), matrix metallopeptidase 8 (MMP8) and body temperature. Dynamics of change of troponin I will be measured additionally.

After ablation each patient will be monitored with ECG telemonitoring system for 7 days.

Detailed Description

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Conditions

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Atrial Fibrillation

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* signed consent;
* criteria for ablation of atrial fibrillation.

Exclusion Criteria

* previous pulmonary veins isolation;
* ablation other than pulmonary veins isolation during the procedure;
* atrial fibrillation at the beginning of ablation procedure;
* usage of 'single shot' devices.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Medical University of Warsaw

OTHER

Sponsor Role lead

Responsible Party

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Marcin Grabowski

Clinical Professor, Marcin Grabowski, Medical University of Warsaw

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Marcin D Grabowski, PhD

Role: STUDY_CHAIR

1st Department of Cardiology Medical University of Warsaw

Paweł Balsam, PhD

Role: STUDY_CHAIR

1st Department of Cardiology Medical University of Warsaw

Piotr Lodziński, PhD

Role: STUDY_CHAIR

1st Department of Cardiology Medical University of Warsaw

Grzegorz Opolski, Professor

Role: STUDY_CHAIR

1st Department of Cardiology Medical University of Warsaw

Locations

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1st Department of Cariology of Medcial University of Warsaw

Warsaw, Masovian Voivodeship, Poland

Site Status RECRUITING

Countries

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Poland

Central Contacts

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Michał Peller, MD

Role: CONTACT

694 914 962 ext. 0048

Krzysztof Ozierański, MD

Role: CONTACT

509 996 947 ext. 0048

Facility Contacts

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Michał Peller, MD

Role: primary

694 914 962 ext. 0048

Krzysztof Ozierański, MD

Role: backup

509 996 947 ext. 0048

Other Identifiers

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KB/143/2016

Identifier Type: -

Identifier Source: org_study_id

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