Novel Coating to Minimize Bacterial Adhesions and Tooth Wear in Denture Acrylic

NCT ID: NCT02834832

Last Updated: 2020-07-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

17 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-11-30

Study Completion Date

2019-07-18

Brief Summary

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This study evaluates the effect of coatings on bacterial adhesion on denture acrylic and the wear of denture teeth.

Detailed Description

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Denture stomatitis is a prevalent disease among removable denture wearers. The cause of this disease stems from a myriad of factors including host immunity and poor oral hygiene. Denture acrylic material is very conducive for the growth and adhesion of bacteria because of its porous nature. The application of plasma enhanced chemical vapor deposited (PECVD) coatings on the surface of acrylic dentures can produce a less porous surface which may minimize the adhesion of bacteria and therefore colonization. The goal is the application of these coatings will help minimize the occurrence of denture stomatitis.

Another issue of removable dentures is the low wear resistance of denture teeth. The application of these coatings on denture teeth should minimize wear of these teeth and prolong the life of removable dentures.

Conditions

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Denture Stomatitis Wear of Denture Teeth

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Control

The patients will be given removable dentures with no coatings. These dentures are part of the standard of care to treat their edentulism.

No interventions assigned to this group

PECVD Coatings

The patients will be given removable partial dentures with PECVD coatings on both the tissue surface of the dentures and the acrylic denture teeth.

PECVD coating

Intervention Type DEVICE

SiO2/SiC coatings will be applied to the surface of removable partial dentures and denture teeth.

Interventions

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PECVD coating

SiO2/SiC coatings will be applied to the surface of removable partial dentures and denture teeth.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Patients who are missing some teeth and will need removable dentures

Exclusion Criteria

* Medical contraindication for dental treatment
Minimum Eligible Age

21 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Florida

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Josephine F. Esquivel-Upshaw, DMD, MS

Role: PRINCIPAL_INVESTIGATOR

University of Florida

Locations

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University of Florida

Gainesville, Florida, United States

Site Status

Countries

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United States

Other Identifiers

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UFirst 5154

Identifier Type: OTHER

Identifier Source: secondary_id

IRB201600805

Identifier Type: -

Identifier Source: org_study_id

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