Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
36 participants
INTERVENTIONAL
2016-07-31
2016-11-30
Brief Summary
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Comparison to patients with arterial disease but absence of lower limb claudication (Cardiac group) feasibility study.
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Detailed Description
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Analysis of the activity of mitochondrial chain Immunochemistry of tissue markers
Conditions
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Study Design
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NON_RANDOMIZED
PARALLEL
BASIC_SCIENCE
SINGLE
Study Groups
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Peripheral artery diseased group
pad Patients referred for femoro popliteal bypass Muscle biopsy during surgery
Muscle Biopsy
A distal and proximal biopsy of the sartorius muscles ( 0.5 cm3 each) will be performed during surgery for saphenous vein withdrawal (cardiac group) or arterial bypass (PAD group) The samples are then treated with neurovascular and mitochondrial biology laboratory.
the activity of the complex 1 is analyzed and compared between the 2 groups.
Cardiac group
Patients referred for saphenous withdrawal for coronary bypass Muscle biopsy during surgery
Muscle Biopsy
A distal and proximal biopsy of the sartorius muscles ( 0.5 cm3 each) will be performed during surgery for saphenous vein withdrawal (cardiac group) or arterial bypass (PAD group) The samples are then treated with neurovascular and mitochondrial biology laboratory.
the activity of the complex 1 is analyzed and compared between the 2 groups.
Interventions
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Muscle Biopsy
A distal and proximal biopsy of the sartorius muscles ( 0.5 cm3 each) will be performed during surgery for saphenous vein withdrawal (cardiac group) or arterial bypass (PAD group) The samples are then treated with neurovascular and mitochondrial biology laboratory.
the activity of the complex 1 is analyzed and compared between the 2 groups.
Eligibility Criteria
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Inclusion Criteria
* Intervention for saphenous withdrawal for coronary bypass surgery (cardiac group)
Exclusion Criteria
* Pregnant woman
18 Years
ALL
No
Sponsors
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University Hospital, Angers
OTHER_GOV
Responsible Party
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Principal Investigators
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Pierre ABRAHAM, PROFESSOR
Role: PRINCIPAL_INVESTIGATOR
UH ANGERS
Locations
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Uh Angers
Angers, , France
Countries
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Other Identifiers
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2013-A00166-39
Identifier Type: -
Identifier Source: org_study_id
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