Evaluation of 4D Magnetic Resonance Flow Sequence at Hepatic Level

NCT ID: NCT02821078

Last Updated: 2025-11-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

44 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-03-16

Study Completion Date

2019-01-24

Brief Summary

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The objective of the project is to establish the 3D velocity mapping of the hepatic vasculature and its consistency

Detailed Description

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The objective of the project is to establish the 3D velocity mapping of the hepatic vasculature and its consistency. Specifically, the investigators will assess the consistency of the quantitative data by measuring hepatic blood Inflow (hepatic artery + portal vein) and outflow (inferior vena cava differential flow). According to the mass conservation physical property, blood inflow must equals blood outflow. The relative gap between the measured values will characterize the consistency of the acquisition.

Conditions

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Magnetic Resonance Imaging

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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Participants

In addition to the standard clinical MR protocol, 2 added sequences:

* 4D flow imaging sequence
* standard 2D-PhaseContrast at portal trunk level as reference

Group Type EXPERIMENTAL

4D flow imaging sequence

Intervention Type OTHER

4D flow imaging sequence

Interventions

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4D flow imaging sequence

4D flow imaging sequence

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Participants have fasted for 6 hours before examination
* Adult participants

Exclusion Criteria

* Anyone with a classic contraindication to MRI
* Recanalized umbilical vein
* Severe obesity
* Gadolinium chelate allergy
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Centre Hospitalier Universitaire, Amiens

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Thierry Yzet, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

CHU Amiens

Locations

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CHU Amiens

Amiens, , France

Site Status

Countries

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France

References

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Yzet T, Bouzerar R, Baledent O, Renard C, Lumbala DM, Nguyen-Khac E, Regimbeau JM, Deramond H, Meyer ME. Dynamic measurements of total hepatic blood flow with Phase Contrast MRI. Eur J Radiol. 2010 Jan;73(1):119-24. doi: 10.1016/j.ejrad.2008.09.032. Epub 2008 Nov 12.

Reference Type RESULT
PMID: 19008062 (View on PubMed)

Other Identifiers

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2016-A00641-50

Identifier Type: OTHER

Identifier Source: secondary_id

PI2016_843_0010

Identifier Type: -

Identifier Source: org_study_id

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