3D High Resolution Manometry and Balloon Expulsion Test in Diagnosis of Dyssynergic Defecation in Children

NCT ID: NCT02812836

Last Updated: 2018-11-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-03-01

Study Completion Date

2019-03-01

Brief Summary

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Anorectal 3D manometry (3D HRAM) is the most advanced version of manometric equipment that measures pressures along the anal canal in a very detailed manner. It provides complete data about pressure profile of anorectum and may indicate impaired defecation dynamics. Balloon expulsion test (BET) is a cheap, easy way to diagnose constipation as the result of outlet obstruction.

Our aim is to compare this two methods of diagnosis of dyssynergic defecation and to find the correlation between this diagnostic equipment.

Detailed Description

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Patients with the diagnosis of constipation will be enrolled in the study. Each patient will be investigated by anorectal manometry and after the procedure BET will be performed at the same day.

During anorectal manometry conventional manometric parameters will be recorded, such as resting pressure, squeeze pressure, bear down manoeuver, thresholds of sensation and threshold of recto anal inhibitory reflex. 3D picture of anal canal will be recorded.

After the manometry standard BET will be performed. The balloon will be inserted into the rectum and patient will be asked to expel it in private during 1 min.

Data from manometry will be correlated with the success rate of BET.

Conditions

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Children Constipation

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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Manometry

All patients will be investigated by anorectal manometry and after the procedure with balloon expulsion test as previously described.

Group Type OTHER

Manometry

Intervention Type DEVICE

Each patient will be investigated first by anorectal manometry, standard protocol of conventional parameters will be recorded such as: resting pressure, squeeze pressure, bear down manoeuver, thresholds of sensation and threshold of recto anal inhibitory reflex. 3D picture of anal canal will be recorded. After that balloon with 50 ml of water will be inserted into the rectum and patient will be asked to expel the device within 1 min in privacy.

Interventions

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Manometry

Each patient will be investigated first by anorectal manometry, standard protocol of conventional parameters will be recorded such as: resting pressure, squeeze pressure, bear down manoeuver, thresholds of sensation and threshold of recto anal inhibitory reflex. 3D picture of anal canal will be recorded. After that balloon with 50 ml of water will be inserted into the rectum and patient will be asked to expel the device within 1 min in privacy.

Intervention Type DEVICE

Other Intervention Names

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Balloon

Eligibility Criteria

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Inclusion Criteria

* Constipation
* Parental agreement

Exclusion Criteria

* after surgery on lower gastrointestinal tract
* diagnosis of inflammatory bowel disease
* diagnosis of other disorder that may affect anorectum function
* parental disagreement
Minimum Eligible Age

5 Years

Maximum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Medtronic

INDUSTRY

Sponsor Role collaborator

Medical University of Warsaw

OTHER

Sponsor Role lead

Responsible Party

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Marcin Banasiuk

PhD

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Marcin Banasiuk, PhD

Role: PRINCIPAL_INVESTIGATOR

Medical University of Warsaw

Locations

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Department of Pediatric Gastroenterology and Nutrition

Warsaw, , Poland

Site Status RECRUITING

Countries

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Poland

Central Contacts

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Marcin Banasiuk, PhD

Role: CONTACT

+48223179463

Facility Contacts

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Marcin Banasiuk, PhD

Role: primary

+48223179463

Other Identifiers

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Banasiuk 2016B

Identifier Type: -

Identifier Source: org_study_id

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