Treating Non-epileptic Seizures Using Magnetic Brain Stimulation
NCT ID: NCT02796924
Last Updated: 2020-09-30
Study Results
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View full resultsBasic Information
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COMPLETED
NA
10 participants
INTERVENTIONAL
2016-06-30
2019-09-30
Brief Summary
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Detailed Description
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Electronic as well as paper-and-pencil questionnaires will be used to asses patient's psychiatric symptoms and functional impairment both before and after treatment to monitor symptom-changes.Treatment will consist of daily sessions of high frequency (20 Hz) rTMS applied over the right temporoparietal junction (TPJ) of the cerebral cortex. Patients will receive two sessions per day for 15 consecutive weekdays. Each session will take approximately 20 minutes to complete.
Results of the questionnaires will be analyzed to determine the effect of the treatment on PNES episodes and functional impairment. As a pilot study, this research will be used to evaluate the effect size and the feasibility of a more definitive project in the future. Both patient response and tolerability to rTMS will be analyzed.
Conditions
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Study Design
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NA
SINGLE_GROUP
TREATMENT
NONE
Study Groups
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Patients
30 sessions of high-frequency (20Hz) repetitive stimulation applied over the right temporal-parietal junction in patients with psychogenic non-epileptic seizures using a MagStim Rapid2 Transcranial Magnetic Simulation machine.
MagStim Rapid2 Transcranial Magnetic Simulation
A non-invasive method of brain stimulation
Interventions
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MagStim Rapid2 Transcranial Magnetic Simulation
A non-invasive method of brain stimulation
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Major comorbid neurological diseases
* Currently taking medications that are known to reduce seizure-threshold
* Currently pregnant
18 Years
ALL
No
Sponsors
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University of Manitoba
OTHER
Responsible Party
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Principal Investigators
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Mandana Modirrousta, MD PhD FRCPC
Role: PRINCIPAL_INVESTIGATOR
University of Manitoba
Provided Documents
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Document Type: Study Protocol and Statistical Analysis Plan
Other Identifiers
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B2016:039
Identifier Type: -
Identifier Source: org_study_id
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