Acceptability, Tolerance, Satiety and Prebiotic Effect of a New Infant Cereal

NCT ID: NCT02781298

Last Updated: 2017-02-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

46 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-12-31

Study Completion Date

2017-02-28

Brief Summary

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This study evaluates a new infant cereals on acceptability, tolerance, satiety and prebiotic effect in infants.

Detailed Description

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This is a controlled, randomized, prospective, crossover, triple-blind study to evaluate of a new infant cereal with a portion of whole grain flour on sensorial acceptability, gastrointestinal tolerance, satiety and prebiotic effect in healthy infants fron 5 to 8 months of age at the beginning of complementary feeding.

Conditions

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Infant Nutrition Sciences

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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New Infant Cereal

amount ingested according to pediatricians recommendations

Group Type EXPERIMENTAL

New Infant Cereal

Intervention Type DIETARY_SUPPLEMENT

The infants will start the complementary feeding with the infants cereals of this study, the amount of cereal ingested will be free according to pediatricians recommendations.

Multicereals Infant Cereal

Intervention Type DIETARY_SUPPLEMENT

The infants will start the complementary feeding with the infants cereals of this study, the amount of cereal ingested will be free according to pediatricians recommendations.

Multicereals Infant Cereal

amount ingested according to pediatricians recommendations

Group Type ACTIVE_COMPARATOR

New Infant Cereal

Intervention Type DIETARY_SUPPLEMENT

The infants will start the complementary feeding with the infants cereals of this study, the amount of cereal ingested will be free according to pediatricians recommendations.

Multicereals Infant Cereal

Intervention Type DIETARY_SUPPLEMENT

The infants will start the complementary feeding with the infants cereals of this study, the amount of cereal ingested will be free according to pediatricians recommendations.

Interventions

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New Infant Cereal

The infants will start the complementary feeding with the infants cereals of this study, the amount of cereal ingested will be free according to pediatricians recommendations.

Intervention Type DIETARY_SUPPLEMENT

Multicereals Infant Cereal

The infants will start the complementary feeding with the infants cereals of this study, the amount of cereal ingested will be free according to pediatricians recommendations.

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* Healthy term infant
* Birth weight 2500-4200 g
* Tolerance to cow's milk
* Tolerance to lactose
* No Breastfeeding at least 4 months of age
* No use antibiotic at least 2 weeks before recruitments

Exclusion Criteria

* Intolerance to gluten (celiac disease)
* Congenital abnormalities
* Acute diseases
* Chronic situation that affect to food intake or metabolism
* Breastfeeding infant
* Any food allergy
* Participation in other study
Minimum Eligible Age

5 Months

Maximum Eligible Age

6 Months

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Universidad de Murcia

OTHER

Sponsor Role collaborator

Hospital Universitario Virgen de la Arrixaca

OTHER

Sponsor Role collaborator

Quantum Experimental

UNKNOWN

Sponsor Role collaborator

Hero Institute for Infant Nutrition

INDUSTRY

Sponsor Role lead

Responsible Party

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Luis Manuel Sanchez Siles

Director Innovation Infant Nutrition

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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David Gil, PhD

Role: PRINCIPAL_INVESTIGATOR

Hospital Virgen de la Arrixaca

Luis M Sánchez, PhD

Role: STUDY_CHAIR

Hero

Locations

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Institute Hero for Infant Nutrition

Alcantarilla, Murcia, Spain

Site Status

Quantum Experimental

Murcia, Murcia, Spain

Site Status

University of Murcia

Murcia, Murcia, Spain

Site Status

Hospital Virgen de la Arrixaca

Murcia, Murcia, Spain

Site Status

Countries

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Spain

References

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Mennella JA, Trabulsi JC. Complementary foods and flavor experiences: setting the foundation. Ann Nutr Metab. 2012;60 Suppl 2(Suppl 2):40-50. doi: 10.1159/000335337. Epub 2012 Apr 27.

Reference Type RESULT
PMID: 22555188 (View on PubMed)

Bernal MJ, Periago MJ, Martinez R, Ortuno I, Sanchez-Solis M, Ros G, Romero F, Abellan P. Effects of infant cereals with different carbohydrate profiles on colonic function--randomised and double-blind clinical trial in infants aged between 6 and 12 months--pilot study. Eur J Pediatr. 2013 Nov;172(11):1535-42. doi: 10.1007/s00431-013-2079-3. Epub 2013 Jun 29.

Reference Type RESULT
PMID: 23812516 (View on PubMed)

Fardet A. New hypotheses for the health-protective mechanisms of whole-grain cereals: what is beyond fibre? Nutr Res Rev. 2010 Jun;23(1):65-134. doi: 10.1017/S0954422410000041. Epub 2010 Jun 22.

Reference Type RESULT
PMID: 20565994 (View on PubMed)

Stephen A, Alles M, de Graaf C, Fleith M, Hadjilucas E, Isaacs E, Maffeis C, Zeinstra G, Matthys C, Gil A. The role and requirements of digestible dietary carbohydrates in infants and toddlers. Eur J Clin Nutr. 2012 Jul;66(7):765-79. doi: 10.1038/ejcn.2012.27. Epub 2012 Apr 4.

Reference Type RESULT
PMID: 22473042 (View on PubMed)

Related Links

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Other Identifiers

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CT09-14

Identifier Type: -

Identifier Source: org_study_id

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