Genetic Basis of Rosacea Study (Control)

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

10 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-01-21

Study Completion Date

2016-08-01

Brief Summary

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Rosacea is a common disease characterized by inflammation and vascular abnormalities of the facial skin and ocular surface. It it considered to be a syndrome encompassing various combinations of cutaneous signs including flushing, erythema, telangiectasia, papules, edema, ocular lesions, and rhinophyma. The exact etiology of cutaneous rosacea is unknown but is characterized by persistent vasodilation, increased vascular permeability, and vascular hyper-reactivity of the microcirculation of the central part of the face. The purpose of this study is to develop gene expression profiles of papulopustular rosacea compared to those of normal skin. The investigator hopes to better understand the abnormal gene functions that might contribute to this condition. This understanding may lead to the development of additional and better treatments for rosacea.

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Detailed Description

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Conditions

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Rosacea

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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Control Group

Participants who do not have rosacea (control group)

Group Type OTHER

Skin Biopsy

Intervention Type OTHER

Skin biopsies will be performed via the Keys punch technique from normal facial skin.

Interventions

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Skin Biopsy

Skin biopsies will be performed via the Keys punch technique from normal facial skin.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

1. Fitzpatrick skin type II or III
2. Age greater than or equal to 18 years
3. Individuals without a history of rosacea

Exclusion Criteria

1. Women who are pregnant or lactating
2. Use of topical prescription medications or procedures to the face within one month of enrollment
3. Skin conditions that might interfere with interpretation of procedure results (at the discretion of the investigator)

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes