Omega-3 Fatty Acids Enriched Food and Microvascular Reactivity

NCT ID: NCT02720250

Last Updated: 2016-03-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-03-31

Study Completion Date

2018-12-31

Brief Summary

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Previous studies have shown that omega-3 fatty acid pills intake have beneficial effect on vascular health in overweight and/or hypertensive patients.

However, there is a lack of studies showing the effect of everyday consumption of omega-3 fatty acids enriched food (not pills) on lipid profile and microvascular reactivity in healthy population.

This study aimed to determine the effect of omega-3 enriched chicken eggs consumption on microvascular reactivity and lipid profile in young healthy subjects.

Detailed Description

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Conditions

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Omega-3 Polyunsaturated Fatty Acids

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Omega-3

Intake of 3 omega-3 fatty acids enriched chicken eggs per day for three weeks.

Group Type EXPERIMENTAL

Omega-3 chicken eggs

Intervention Type DIETARY_SUPPLEMENT

Intake of 3 omega-3 fatty acids enriched chicken eggs per day for three weeks.

Regular

Intake of 3 regular chicken eggs per day for three weeks.

Group Type EXPERIMENTAL

Regular chicken eggs

Intervention Type DIETARY_SUPPLEMENT

Intake of 3 regular chicken eggs per day for three weeks.

Interventions

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Omega-3 chicken eggs

Intake of 3 omega-3 fatty acids enriched chicken eggs per day for three weeks.

Intervention Type DIETARY_SUPPLEMENT

Regular chicken eggs

Intake of 3 regular chicken eggs per day for three weeks.

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

\- healthy volunteers

Exclusion Criteria

* oral contraceptives
* drugs that could affect endothelium
* hypertension
* coronary artery disease
* diabetes
* hyperlipidaemia
* renal impairment
* cerebrovascular and peripheral artery disease
Minimum Eligible Age

18 Years

Maximum Eligible Age

35 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Josip Juraj Strossmayer University of Osijek

OTHER

Sponsor Role lead

Responsible Party

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Ines Drenjancevic

Vice Dean for Science, Faculty of Medicine Josip Juraj Strossmayer University of Osijek

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Ines Drenjancevic, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Faculty of Medicine, University of Osijek, Croatia

Locations

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Faculty of Medicine Osijek, Laboratory for Clinical and Sport Physiology

Osijek, , Croatia

Site Status RECRUITING

Countries

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Croatia

Central Contacts

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Ana Stupin, MD, PhD

Role: CONTACT

+385915134958

Ines Drenjancevic, MD, PhD

Role: CONTACT

+385912241406

Facility Contacts

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Ana Stupin, MD, PhD

Role: primary

'385915134598

Ines Drenjancevic, MD, PhD

Role: backup

'385912241406

References

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Cavka A, Cosic A, Jukic I, Jelakovic B, Lombard JH, Phillips SA, Seric V, Mihaljevic I, Drenjancevic I. The role of cyclo-oxygenase-1 in high-salt diet-induced microvascular dysfunction in humans. J Physiol. 2015 Dec 15;593(24):5313-24. doi: 10.1113/JP271631. Epub 2015 Dec 7.

Reference Type BACKGROUND
PMID: 26498129 (View on PubMed)

Other Identifiers

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2158610714114

Identifier Type: -

Identifier Source: org_study_id

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