Evaluation of Performance of Automatic Fusion for Radiofrequency Ablation of Hepatocellular Carcinoma

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

82 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-12-31

Study Completion Date

2017-03-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Fusion imaging of US and MRI is very helpful for interventional procedure such as radiofrequency ablation in liver. However, manual registration of US and magnetic resonance (MR) imaging is somewhat time-consuming and difficult for less-experienced physicians. Recently, automatic registration function was developed to help the fusion of US and CT/MRI imaging. The purpose of this trial is to compare the registration time and accuracy of manual registration system and automatic registration system.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Pre-procedure Planning for Radiofrequency Ablation Using CT or MR/US Fusion

NCT02687113

Liver Cancer

COMPLETED NA

Pre-procedure Planning for Liver Biopsy or Radiofrequency Ablation Using CT or MR/US Fusing Imaging

NCT02967198

Liver Mass Liver Fibroses

COMPLETED NA

CT/MR-US Automatic Fusion System in Pre-procedure Planning for Radiofrequency Ablation

NCT04844112

Hepatocellular Carcinoma

COMPLETED NA

Added Value of Contrast-enhanced Ultrasonography for Percutaneous Radiofrequency Ablation

NCT05445973

Radiofrequency Ablation Ultrasonography Liver Tumors

COMPLETED NA

Safety Margin Assessment After RFA Using the Registration of Pre-ablation MRI and Post-ablation CT

NCT02985034

HCC Liver Tumor

COMPLETED

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

1. Patients will be randomized and assigned.
2. For automatic registration group, automatic image fusion will be done by RS80A US unit and RF ablation will be performed. Image fusion time will be measured.
3. For manual registration group, manual image fusion will be done by LOGIQ-E9 US unit and RF ablation will be performed. Image fusion time will be measured.

3\) After radiofrequency (RF) ablation, immediate, contrast enhanced CT will be performed to evaluate technical success and complications 4) Accuracy of registration will be measured by home-made software using 3D techniques.

5\) After one month, technical effectiveness will be evaluated by contrast enhanced CT 6) F/U of CT images will be obtained until one year after RF ablation with a interval of 1-3 months.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Hepatocellular Carcinoma

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Automatic registration arm

Automatic registration for fusion imaging of US and MRI will be performed.

Automatic Imaging fusion of ultrasonography and MRI

Group Type EXPERIMENTAL

Automatic Imaging fusion of ultrasonography and MRI

Intervention Type DEVICE

Radiofrequency ablation for hepatic malignancies will be performed with automatic registration registration. Except the imaging registration, all other procedures for RF ablation is same.

Manual registration arm

Manual registration for fusion imaging of US and MRI will be performed.

Manual Imaging fusion of ultrasonography and MRI

Group Type ACTIVE_COMPARATOR

Manual Imaging fusion of ultrasonography and MRI

Intervention Type DEVICE

Radiofrequency ablation for hepatic malignancies will be performed with manual registration registration. Except the imaging registration, all other procedures for RF ablation is same.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Automatic Imaging fusion of ultrasonography and MRI

Radiofrequency ablation for hepatic malignancies will be performed with automatic registration registration. Except the imaging registration, all other procedures for RF ablation is same.

Intervention Type DEVICE

Manual Imaging fusion of ultrasonography and MRI

Radiofrequency ablation for hepatic malignancies will be performed with manual registration registration. Except the imaging registration, all other procedures for RF ablation is same.

Intervention Type DEVICE