Incidence of Intracranial Hypertension During Liver Transplantation Estimated by Non-invasive Ultrasound Methods.
NCT ID: NCT02695823
Last Updated: 2018-12-21
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
29 participants
INTERVENTIONAL
2015-12-09
2017-03-31
Brief Summary
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The invasive monitoring of the intracranial pressure is not used in these patients, due to a high risk of infection and bleeding. The non-invasive monitoring of intracranial pressure has been widely developed in recent years : transcranial doppler and recently ultrasound of the optic nerve sheath (ONSD) allow an effective detection of intracranial hypertension.
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Detailed Description
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Conditions
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Study Design
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NA
SINGLE_GROUP
DIAGNOSTIC
NONE
Study Groups
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Patients undergoing liver transplantation
Ultrasound
Ultrasound measurements of the optic nerve sheath diameter and intracranial Doppler, at 4 time points during surgery (incision, anhepatic phase + 30 min, declamping + 5 min, declamping + 30 min), and at day 1 and day 5 after surgery, to detect presence of intracranial hypertension.
Search of any neurological complication during the 5 postoperative days.
Interventions
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Ultrasound
Ultrasound measurements of the optic nerve sheath diameter and intracranial Doppler, at 4 time points during surgery (incision, anhepatic phase + 30 min, declamping + 5 min, declamping + 30 min), and at day 1 and day 5 after surgery, to detect presence of intracranial hypertension.
Search of any neurological complication during the 5 postoperative days.
Eligibility Criteria
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Inclusion Criteria
* Patients who underwent orthotopic liver transplantation
* Patients who have received clear information and not opposed to participate in the study
* Patients affiliated to a social security scheme or similar
* Patients not undergoing a measure of legal protection
Exclusion Criteria
* Patients \< 18 years
* Pregnant women or breastfeeding
* Deprived of individual liberty
* Non-affiliated to a social security scheme
* Known ophthalmic pathology: untreated cataracts, glaucoma
18 Years
ALL
No
Sponsors
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Hospices Civils de Lyon
OTHER
Responsible Party
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Principal Investigators
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Mathieu GAZON, MD
Role: PRINCIPAL_INVESTIGATOR
Hospices Civils de Lyon
Locations
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Département d'anesthésie réanimation
Lyon, , France
Countries
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Other Identifiers
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69HCL15_0483
Identifier Type: -
Identifier Source: org_study_id
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