Recurrent Failures in assIsted Reproductive Techniques (The FIRST Registry)
NCT ID: NCT02685800
Last Updated: 2019-01-31
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
624 participants
OBSERVATIONAL
2015-10-31
2020-09-30
Brief Summary
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A possible role for inherited and acquired thrombophilias has been invoked, especially in women with previous implantation failures. However, several factors could play a role in these conditions.
A potential benefit of low-molecular-weight heparin (LMWH) in improving ART outcomes, independently of the presence of thrombophilia, has been recently suggested.
This register is designed in order to better define all possible variables influencing ART outcome and improve clinical management of women with previous implantation failures. During this study the investigators will collect and evaluate clinical data regarding the first cycle in women with previous ART failures.
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Eligibility Criteria
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Inclusion Criteria
* ART cycle at enrolment
* Informed consent
Exclusion Criteria
* Uterine pathology
* Hydrosalpinges
* Previous inclusion in the study
18 Years
45 Years
FEMALE
No
Sponsors
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Casa Sollievo della Sofferenza IRCCS
OTHER
Responsible Party
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Elvira Grandone, MD, Head of Unit
Head of Unit
Principal Investigators
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Elvira Grandone
Role: PRINCIPAL_INVESTIGATOR
IRCCS Casa Sollievo della Sofferenza - San Giovanni Rotondo, Foggia, Italy
Locations
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IRCCS Casa Sollievo della Sofferenza
San Giovanni Rotondo, Foggia, Italy
Countries
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Central Contacts
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Facility Contacts
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Elvira Grandone
Role: primary
References
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Villani M, Baldini D, Totaro P, Larciprete G, Kovac M, Carone D, Passamonti SM, Permunian ET, Bartolotti T, Lojacono A, Cacciola R, Pinto GL, Bucherini E, De Stefano V, Lodigiani C, Lavopa C, Cho YS, Pizzicaroli C, Colaizzo D, Grandone E. Rationale and design of two prospective, multicenter, observational studies on reproductive outcome in women with recurrent failures after spontaneous or assisted conception: OTTILIA and FIRST registries. BMC Pregnancy Childbirth. 2019 Aug 13;19(1):292. doi: 10.1186/s12884-019-2444-y.
Other Identifiers
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FIRST - V 1_28 Ago 15
Identifier Type: -
Identifier Source: org_study_id
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