Factors and Perceptions Affecting Treatment Choices of Breast Cancer Patients

NCT ID: NCT02679638

Last Updated: 2016-02-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

450 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-02-29

Study Completion Date

2017-05-31

Brief Summary

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A Multi-center Cross-sectional quantitative study with a preliminary qualitative study part aiming to identify and analyze demand factors, supply factors and perceptions affecting Breast Cancer patients' treatment choices of Breast Cancer patients in 5 key decision points: participation role in the decision making process, hospital choice, treatment regimen choice, surgical extent and surgeon choice. 25 patients and caregivers will participate in the qualitative part and 425 Israeli Breast Cancer patients will participate in the quantitative study.

Detailed Description

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Background:

Breast Cancer (BC) is the most common cancer in women worldwide. Newly diagnosed BC patients are asked to participate in a number of treatment related decisions. No research has systematically studied the full decision sequence in a disease such as BC, analyzing demand factors, supply factors and patient perceptions.

Study goal:

Identify and analyze demand factors, supply factors and perceptions affecting BC patients' treatment choices, and model the demand function of BC patients in 5 key decision points: participation role in the decision making process, hospital choice, treatment regimen choice, surgical extent and surgeon choice.

Study hypothesis: Patient perceptions will have at least as much impact as demand and supply factors.

Study design:

Two stage study. A preliminary qualitative study, holding depth interviews with 20 breast cancer patients, 2 spouses and 3 staff members is taking place these days. The qualitative study findings will be used to develop a survey questionnaire for a cross sectional quantitative study, interviewing a quota sample of 425 breast cancer survivors, diagnosed up to 5 years prior to joining the study, who have successfully completed all radiation therapy and chemotherapy.

Data analysis:

Qualitative data will be analyzed according to the Criteria Bases Qualitative Methodology. Quantitative data will be analyzed by two-variable statistical analysis and multi-variable statistical analysis adjusted to the nature of the dependent and independent variables.

Possible policy recommendations:

Forming consulting teams for cancer patients. Improving medical information communication. Focusing patients on the key decisions they face. Evaluating patient needs using demand factors, supply factors and perceptions to create systemic tools helping them face treatment decisions.

Conditions

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Breast Cancer

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Kaplan Hospital

Breast cancer survivors recruited at the Kaplan Medical Center

Factors and perceptions questionnaire

Intervention Type OTHER

A detailed questionnaire inquiring about demand factors, supply factors and perceptions affecting patients' treatment choices in 5 key decision points: participation role in the decision making process, hospital choice, treatment regimen choice, surgical extent and surgeon choice.

Qualitative interview

Intervention Type OTHER

Depth interviews with 20 breast cancer patients, 2 spouses and 3 staff members.

Rambam Hospital

Breast cancer survivors recruited at the Rambam Medical Center

Factors and perceptions questionnaire

Intervention Type OTHER

A detailed questionnaire inquiring about demand factors, supply factors and perceptions affecting patients' treatment choices in 5 key decision points: participation role in the decision making process, hospital choice, treatment regimen choice, surgical extent and surgeon choice.

Qualitative interview

Intervention Type OTHER

Depth interviews with 20 breast cancer patients, 2 spouses and 3 staff members.

Sheba

Breast cancer survivors recruited at the Sheba Medical Center

Factors and perceptions questionnaire

Intervention Type OTHER

A detailed questionnaire inquiring about demand factors, supply factors and perceptions affecting patients' treatment choices in 5 key decision points: participation role in the decision making process, hospital choice, treatment regimen choice, surgical extent and surgeon choice.

Barzilai

Breast cancer survivors recruited at the Barzilai Medical Center

Factors and perceptions questionnaire

Intervention Type OTHER

A detailed questionnaire inquiring about demand factors, supply factors and perceptions affecting patients' treatment choices in 5 key decision points: participation role in the decision making process, hospital choice, treatment regimen choice, surgical extent and surgeon choice.

Interventions

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Factors and perceptions questionnaire

A detailed questionnaire inquiring about demand factors, supply factors and perceptions affecting patients' treatment choices in 5 key decision points: participation role in the decision making process, hospital choice, treatment regimen choice, surgical extent and surgeon choice.

Intervention Type OTHER

Qualitative interview

Depth interviews with 20 breast cancer patients, 2 spouses and 3 staff members.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Hebrew speaking Jewish women
* Aged 30 - 75 years
* Diagnosed with breast cancer up to 5 years prior to study recruitment
* Successfully completed all chemotherapy and radiotherapy treatments
* Considered Cancer free

Exclusion Criteria

* Any type of residual cancer
* Any type of chemotherapy or radiotherapy
Minimum Eligible Age

30 Years

Maximum Eligible Age

75 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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University of Haifa

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Shuli Brammli-Greenberg, PhD

Role: STUDY_CHAIR

Head of the Master of Public Health Program at Haifa University

Central Contacts

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Shuli Brammli-Greenberg, PhD

Role: CONTACT

+972508159054

Boaz Hovav, MD

Role: CONTACT

+972543166653

References

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Adams EK, Houchens R, Wright GE, Robbins J. Predicting hospital choice for rural Medicare beneficiaries: the role of severity of illness. Health Serv Res. 1991 Dec;26(5):583-612.

Reference Type RESULT
PMID: 1743970 (View on PubMed)

Beaver K, Luker KA, Owens RG, Leinster SJ, Degner LF, Sloan JA. Treatment decision making in women newly diagnosed with breast cancer. Cancer Nurs. 1996 Feb;19(1):8-19. doi: 10.1097/00002820-199602000-00002.

Reference Type RESULT
PMID: 8904382 (View on PubMed)

Benbassat J, Pilpel D, Tidhar M. Patients' preferences for participation in clinical decision making: a review of published surveys. Behav Med. 1998 Summer;24(2):81-8. doi: 10.1080/08964289809596384.

Reference Type RESULT
PMID: 9695899 (View on PubMed)

Bouche G, Migeot V, Mathoulin-Pelissier S, Salamon R, Ingrand P. Breast cancer surgery: do all patients want to go to high-volume hospitals? Surgery. 2008 Jun;143(6):699-705. doi: 10.1016/j.surg.2008.03.013. Epub 2008 May 9.

Reference Type RESULT
PMID: 18549885 (View on PubMed)

Celaya MO, Rees JR, Gibson JJ, Riddle BL, Greenberg ER. Travel distance and season of diagnosis affect treatment choices for women with early-stage breast cancer in a predominantly rural population (United States). Cancer Causes Control. 2006 Aug;17(6):851-6. doi: 10.1007/s10552-006-0025-7.

Reference Type RESULT
PMID: 16783613 (View on PubMed)

Duric V, Stockler M. Patients' preferences for adjuvant chemotherapy in early breast cancer: a review of what makes it worthwhile. Lancet Oncol. 2001 Nov;2(11):691-7. doi: 10.1016/S1470-2045(01)00559-9.

Reference Type RESULT
PMID: 11902540 (View on PubMed)

Harris KM. How do patients choose physicians? Evidence from a national survey of enrollees in employment-related health plans. Health Serv Res. 2003 Apr;38(2):711-32. doi: 10.1111/1475-6773.00141.

Reference Type RESULT
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Hawley ST, Griggs JJ, Hamilton AS, Graff JJ, Janz NK, Morrow M, Jagsi R, Salem B, Katz SJ. Decision involvement and receipt of mastectomy among racially and ethnically diverse breast cancer patients. J Natl Cancer Inst. 2009 Oct 7;101(19):1337-47. doi: 10.1093/jnci/djp271. Epub 2009 Aug 31.

Reference Type RESULT
PMID: 19720966 (View on PubMed)

Jansen SJ, Otten W, Stiggelbout AM. Review of determinants of patients' preferences for adjuvant therapy in cancer. J Clin Oncol. 2004 Aug 1;22(15):3181-90. doi: 10.1200/JCO.2004.06.109.

Reference Type RESULT
PMID: 15284271 (View on PubMed)

Katz SJ, Lantz PM, Janz NK, Fagerlin A, Schwartz K, Liu L, Deapen D, Salem B, Lakhani I, Morrow M. Patient involvement in surgery treatment decisions for breast cancer. J Clin Oncol. 2005 Aug 20;23(24):5526-33. doi: 10.1200/JCO.2005.06.217.

Reference Type RESULT
PMID: 16110013 (View on PubMed)

Keating NL, Guadagnoli E, Landrum MB, Borbas C, Weeks JC. Treatment decision making in early-stage breast cancer: should surgeons match patients' desired level of involvement? J Clin Oncol. 2002 Mar 15;20(6):1473-9. doi: 10.1200/JCO.2002.20.6.1473.

Reference Type RESULT
PMID: 11896094 (View on PubMed)

Nelson JA, Tchou J, Domchek S, Sonnad SS, Serletti JM, Wu LC. Breast reconstruction in bilateral prophylactic mastectomy patients: factors that influence decision making. J Plast Reconstr Aesthet Surg. 2012 Nov;65(11):1481-9. doi: 10.1016/j.bjps.2012.05.001. Epub 2012 May 27.

Reference Type RESULT
PMID: 22640643 (View on PubMed)

Rees CE, Bath PA. The information needs and source preferences of women with breast cancer and their family members: a review of the literature published between 1988 and 1998. J Adv Nurs. 2000 Apr;31(4):833-41. doi: 10.1046/j.1365-2648.2000.01341.x.

Reference Type RESULT
PMID: 10759979 (View on PubMed)

Simes RJ, Coates AS. Patient preferences for adjuvant chemotherapy of early breast cancer: how much benefit is needed? J Natl Cancer Inst Monogr. 2001;(30):146-52. doi: 10.1093/oxfordjournals.jncimonographs.a003453.

Reference Type RESULT
PMID: 11773309 (View on PubMed)

Tropman SE, Ricketts TC, Paskett E, Hatzell TA, Cooper MR, Aldrich T. Rural breast cancer treatment: evidence from the Reaching Communities for Cancer Care (REACH) project. Breast Cancer Res Treat. 1999 Jul;56(1):59-66. doi: 10.1023/a:1006279117650.

Reference Type RESULT
PMID: 10517343 (View on PubMed)

Degner LF, Sloan JA, Venkatesh P. The Control Preferences Scale. Can J Nurs Res. 1997 Fall;29(3):21-43.

Reference Type RESULT
PMID: 9505581 (View on PubMed)

Other Identifiers

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27-15

Identifier Type: -

Identifier Source: org_study_id

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