Study on Ultrapro vs Polypropylene: Early Results From a Multicentric Experience in Surgery for Hernia

NCT ID: NCT02666040

Last Updated: 2016-01-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

1200 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-11-30

Study Completion Date

2016-03-31

Brief Summary

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With reference to inguinal hernia surgeries with prosthesis, the multicenter study aims to investigate the benefits in terms of incidence of pain and discomfort, improvement in the quality of life for the patient after the use of the newly introduced semi-absorbable prosthesis (ULTRAPRO® meshes) compared with the prosthesis of totally nonabsorbable material (conventional meshes in polypropylene "Prolene®"), and in terms of the costs for the hospital, the National Health System (NHS), and the society of associates for the use of the ULTRAPRO® in inguinal hernia surgeries.

Detailed Description

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Conditions

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Chronic Pain

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

SINGLE

Participants

Study Groups

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U - ULTRAPRO

Inguinal Hernia Surgery with ULTRAPRO® meshes, a new ULTRAPRO® mesh will be implanted in patients in the group (AG). The surgery will be evaluated in terms of procedure, detecting the mode of admission to hospital, the duration of surgery, anesthesia volume and type used, composition of the surgical equipment.

Group Type EXPERIMENTAL

ULTRAPRO® meshes

Intervention Type DEVICE

The inguinal hernia repair has to be performed with the Lichtenstein technique, with standardized prosthesis fixation and no use of plug.

Detecting the mode of admission to hospital

Intervention Type PROCEDURE

Ordinary admission or day surgery

Duration of surgery

Intervention Type PROCEDURE

Time operating room

Anesthesia volume and type used

Intervention Type PROCEDURE

Anesthesias used: infiltration, followed by spinal, general, epidural.

P - Prolene

Inguinal Hernia Surgery with "Prolene®" meshes, the conventional mesh in polypropylene "Prolene®" will be implanted in patients in the control group (CG). The surgery will be evaluated in terms of procedure, detecting the mode of admission to hospital, the duration of surgery, anesthesia volume and type used, composition of the surgical equipment.

Group Type ACTIVE_COMPARATOR

"Prolene®" meshes

Intervention Type DEVICE

The inguinal hernia repair has to be performed with the Lichtenstein technique, with standardized prosthesis fixation and no use of plug.

Detecting the mode of admission to hospital

Intervention Type PROCEDURE

Ordinary admission or day surgery

Duration of surgery

Intervention Type PROCEDURE

Time operating room

Anesthesia volume and type used

Intervention Type PROCEDURE

Anesthesias used: infiltration, followed by spinal, general, epidural.

Interventions

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ULTRAPRO® meshes

The inguinal hernia repair has to be performed with the Lichtenstein technique, with standardized prosthesis fixation and no use of plug.

Intervention Type DEVICE

"Prolene®" meshes

The inguinal hernia repair has to be performed with the Lichtenstein technique, with standardized prosthesis fixation and no use of plug.

Intervention Type DEVICE

Detecting the mode of admission to hospital

Ordinary admission or day surgery

Intervention Type PROCEDURE

Duration of surgery

Time operating room

Intervention Type PROCEDURE

Anesthesia volume and type used

Anesthesias used: infiltration, followed by spinal, general, epidural.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Elective surgery
* Males and females
* Adults over 18
* All primitive inguinal hernia

Exclusion Criteria

* Emergency surgery
* Impossibility to complete the follow-up
* Patients with acquired immunodeficiency symptoms
* Patients with relapsed inguinal hernia
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Zeta Research Ltd

INDUSTRY

Sponsor Role collaborator

Istituto Clinico Humanitas

OTHER

Sponsor Role lead

Responsible Party

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Michele Tedeschi

Clinical Research Coordinator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Marco Montorsi, Prof.

Role: PRINCIPAL_INVESTIGATOR

Humanitas Research Hospital IRCCS, Rozzano-Milan

Other Identifiers

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10-v035

Identifier Type: -

Identifier Source: org_study_id

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