Embryonal Tumors of Infancy & Childhood: South Egypt Cancer Institute Experience

NCT ID: NCT02665676

Last Updated: 2023-07-24

Basic Information

• Recruitment Status: UNKNOWN
• Total Enrollment: 420 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2019-07-01
• Study Completion Date: 2024-04-30

Brief Summary

The aim of this study is to investigate demographic & disease characteristics of pediatric cancer patients diagnosed with one of embryonal tumors to identify the prevalence, the spectrum of these disease entities & treatment outcomes in these patients.

Detailed Description

Background:

Embryonal tumors arise from cells that are normally present in the developing embryo and originate in developing tissues and organ systems. These tumors occur almost exclusively in children, and are usually diagnosed in children before age 5 years.

The group is heterogeneous and includes relatively common pediatric tumors as well as rare tumors. Three common types of embryonal tumors in children are neuroblastoma, Wilms tumor (WT), and retinoblastoma. Other embryonal tumors, include medulloblastoma and rhabdomyosarcoma.

Patients & Methods:

From January 2001 to December 2015, retrieval & analysis of the medical records of pediatric patients with embryonal tumors will be made at the pediatric oncology department, South Egypt Cancer Institute which represents the largest referral center in Upper Egypt. These data will be categorized according to demographic characteristics, clinico-pathologic features, treatment modalities received, and outcomes of treatments in these patients.

Conditions

Neoplasms, Embryonal; Embryonal Neoplasms

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: RETROSPECTIVE

Eligibility Criteria

Inclusion Criteria

• Patients whose age less than or equal to 18 years.
• Patients diagnosed with any of embryonal neoplasms.

Exclusion Criteria

• Patients whose age more than 18 years.

• Maximum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Assiut University

OTHER

Sponsor Role: lead

Responsible Party

Ahmed Mohammed Morsy, MD

Lecturer, Pediatric Oncology Department

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Assiut University

Asyut, , Egypt

Site Status: RECRUITING

Countries

Egypt

Facility Contacts

Ahmed M. Morsy, MD

Role: primary

ahmedmohammed7829@yahoo.com

+2 01003314522

References

Tulla M, Berthold F, Graf N, Rutkowski S, von Schweinitz D, Spix C, Kaatsch P. Incidence, Trends, and Survival of Children With Embryonal Tumors. Pediatrics. 2015 Sep;136(3):e623-32. doi: 10.1542/peds.2015-0224.

Reference Type: BACKGROUND

PMID: 26304823 (View on PubMed)

Ward E, DeSantis C, Robbins A, Kohler B, Jemal A. Childhood and adolescent cancer statistics, 2014. CA Cancer J Clin. 2014 Mar-Apr;64(2):83-103. doi: 10.3322/caac.21219. Epub 2014 Jan 31.

Reference Type: BACKGROUND

PMID: 24488779 (View on PubMed)

Other Identifiers

Ped Embryonal Tumors SECI

Identifier Type: -

Identifier Source: org_study_id