Assesment of Salivary Alpha-amylase Levels Before and After Ovulation

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-01-31

Study Completion Date

2016-03-31

Brief Summary

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Investigators aimed to investigate whether there is an association between ovulation and salivatory alpha amylase (sAA) activity in menstrual cycles during a month period in a group of reproductive women.

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Detailed Description

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Saliva is a readily available specimen, which can be collected by noninvasive procedures and contains many hormones, drugs and antibodies of interest in screening and diagnosis. With a salivary specimen, one can collect multiple specimens at the optimum times for diagnostic information. Saliva can be collected in remote sites by unskilled personnel and, is stable at ambient temperatures for several weeks. Because of diurnal and monthly variations, several steroid hormones need multiple samples collected early in the morning or late at night or at the same time every day for a month to give meaningful results. Such collections are often very expensive, inconvenient or impossible to do with blood.

Investigators aimed to investigate whether there is an association between ovulation and salivatory alpha amylase (sAA) activity in menstrual cycles during a month period in a group of reproductive women.

Conditions

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Salivary Amylase

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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study group

Reproductive age women with polycystic ovary syndrome and irregular menses (Salivary Alpha-amylase Levels of 3rd and 24th day of menstrual cyclus)

Salivary alpha-Amylases

Intervention Type OTHER

Investigators will collect Salivary alpha-Amylases before and after ovulation

control group

Reproductive age women with regular menses (Salivary Alpha-amylase level of 3rd and 24th day of menstrual cyclus)

Salivary alpha-Amylases

Intervention Type OTHER

Investigators will collect Salivary alpha-Amylases before and after ovulation

Interventions

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Salivary alpha-Amylases

Investigators will collect Salivary alpha-Amylases before and after ovulation

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Clinical diagnosis of PCOS (study group)
* Reproductive age regular menses women

Exclusion Criteria

* pregnancy,
* breastfeeding,
* known liver disease,
* alcohol abuse,
* diabetes mellitus,
* smoking
* treatment with oral glucocorticoids
* treatment with hormonal contraceptives.

Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes