The Effect of Sildenafil Citrate on the Success Rate of Ovulation Induction Using Clomiphene
NCT ID: NCT02663830
Last Updated: 2017-08-16
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE2
210 participants
INTERVENTIONAL
2016-01-10
2017-03-12
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
CROSSOVER
TREATMENT
SINGLE
Study Groups
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(Sildenafil & clomiphene citrate group)
105 Patients will receive 25 mg sildenafil citrate 6 hourly orally (day 6 to the end of the cycle), and clomiphene citrate 100 mg/day (day 2 to 6) orally by the patient, for induction of ovulation
Sildenafil & clomiphene citrate
105 Patients will receive 25 mg sildenafil citrate 6hourly orally (day 6 to the end of the cycle), and clomiphene citrate 100 mg/day (day 2 to 6) orally by the patient, for induction of ovulation
clomiphene only
105 patients will receive only clomiphene citrate 100mg/day (day 2 to 6) orally (2 tablets at same time daily).
clomiphene only
105 Patients will receive clomiphene citrate 100 mg/day (day 2 to 6) orally by the patient, for induction of ovulation
Interventions
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Sildenafil & clomiphene citrate
105 Patients will receive 25 mg sildenafil citrate 6hourly orally (day 6 to the end of the cycle), and clomiphene citrate 100 mg/day (day 2 to 6) orally by the patient, for induction of ovulation
clomiphene only
105 Patients will receive clomiphene citrate 100 mg/day (day 2 to 6) orally by the patient, for induction of ovulation
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Anovulatory cycles due to polycystic ovaries syndrome.
* Non-smokers.
* Free of major medical illness
Exclusion Criteria
* Women with congenital uterine anomaly.
* Chronic use of any medications including non-steroidal anti-inflammatory drugs.
* Associated cases of infertility other than PCOs (male factor, tubal factor,….).
* Asherman syndrome.
* Cases with endometrial hyperplasia.
* Cases with endometrial polyp
21 Years
35 Years
FEMALE
No
Sponsors
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Ain Shams University
OTHER
Responsible Party
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Ahmed Abdel Shafy El Shahawy
Lecturer
Other Identifiers
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SIOO
Identifier Type: -
Identifier Source: org_study_id
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