Effects Oxygen Supplementation Determined Better Exercise Capacity in Eisenmenger Syndrome

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-01-31

Study Completion Date

2014-06-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of this study was to evaluate the acute effects of oxygen supplementation during a submaximal exercise test in patients with Eisenmenger's Syndrome.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Six Minutes Walk Test and Shuttle Walk Test in Eisenmenger Syndrome

NCT02752399

Eisenmenger Complex Pulmonary Hypertension Congenital Heart Defects

UNKNOWN

Effects of Inspiratory Muscle Training on Cardiovascular Function in Hypertension.

NCT01250444

Reduction of Blood Pressure in Hypertensive Patients. Improvement of Cardiovascular Autonomic Control. Improvement of Functional Capacity. +1 more

UNKNOWN NA

Influence of an Inspiratory Muscle Fatigue Protocol on Older Adults on Respiratory Muscle Strength, Muscle Oxygen Saturation, and Functional Capacity

NCT06266013

Healthy

NOT_YET_RECRUITING NA

Effects of Different Protocols of Physical Training on Levels of Muscle Strength and Functional Capacity

NCT03092336

Peripheral Arterial Disease

UNKNOWN NA

Inspiratory Muscle Strength Training in Post-Covid Syndrome

NCT06091384

Cardiovascular Abnormalities Post-COVID-19 Syndrome Physical Exercise

UNKNOWN NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Patients with Eisenmenger's syndrome were submitted to a submaximal exercise test (six-minute walking test) with and without supplemental oxygen. The distance walked during the two tests were compared to assess the impact of oxygen supplementation on the walking distance.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Eisenmenger Complex Hypertension, Pulmonary

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Oxygen Supplementation

Two six-minute walk tests, one with oxygen supplementation and another without were performed on different days. During the test with oxygen supplementation the delivery was continuous by mask at 40% and technician walked behind the patient with the oxygen source.

Group Type EXPERIMENTAL

Oxygen Supplementation

Intervention Type OTHER

Oxygen delivery was continuous by mask at 40%

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Oxygen Supplementation

Oxygen delivery was continuous by mask at 40%

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Abscence of heart failure and/or respiratory infection
* Advanced therapy for pulmonary hypertension

Exclusion Criteria

* Lung, liver or connective tissue diseases
* Neuromuscular diseases
* Inability to perform a pulmonary function test and/or chronic lung disease
* Inability to walk

Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No