Is Routine Use of Histopathological Examination Necessary After Cholecystectomy ?

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

1000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-12-31

Study Completion Date

2018-05-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Cholecystectomy has been made with benign conditions usually. The aim of this study is to compare the macroscopic evaluations of the cholecystectomy specimens with it's histopathological examinations.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Post-ERCP Cholecystectomy. How ERCP and ERCP-related Variables Effect the Outcomes?

NCT06388525

Endoscopic Retrograde Cholangiopancreatography ERCP-Laparoscopic Cholecystectomy Interval Number of Preoperative ERCPs +3 more

COMPLETED

Osmaniye State Hospital"

NCT06511271

Laparoscopic Cholecystectomy

COMPLETED NA

Evaluation of Risk Factors Leading to Conversion From Laparoscopic Cholecystectomy to Open Surgery

NCT06244589

Cholelithiasis Cholecystitis, Acute Cholecystitis, Chronic +1 more

COMPLETED NA

Metabolic Dysfunction Associated Fatty Liver Disease in Long-Term Cholecystectomy Patients

NCT06443723

Liver Steatoses

COMPLETED NA

Effect Of Early Versus Delayed Laparoscopic Cholecystectomy In Patients With Grade II Cholecystitis

NCT05352087

Cholecystitis

COMPLETED NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Cholecystectomy is one of the most frequently performed surgery in the world and often made with benign conditions. Routinely cholecystectomy specimens sent for histopathologic examination. The histopathologic examination of the cholecystectomy specimens are benign in most of the cases and the incidental malignancy of the gallbladder is 2-2.9% in the literature. The histopathologic evaluations of the gallbladder come with additional workload for pathology and surgery departments. Also there is additional cost for the patients. Because of that the idea of selective histopathologic examination has been raised.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Cholelithiasis

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Benign

Benign pathology specimens with macroscopically

No interventions assigned to this group

Suspicious

Suspicious group includes the conditions such as increasing of the gallbladder wall thickness, having calcifications or polyps in the gallbladder.

No interventions assigned to this group

Malign

Malign group includes the conditions such as detecting mass or irregularities in the gallbladder wall.

No interventions assigned to this group

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Subject has cholelithiasis

Exclusion Criteria

* Subject has acute cholecystitis
* Subject has perforated gallbladder
* Subject has malignancy
* Subject has polyps in the gallbladder
* Subject has increasing wall thickness of the gallbladder
* Subject has malignancy in the preoperative ultrasonography in the gallbladder
* Subject has pregnancy

Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No