Effectiveness of Qufeng Shengshi Fang on Treatment of Allergic Rhinitis.

NCT ID: NCT02653339

Last Updated: 2016-04-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

180 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-06-30

Study Completion Date

2018-08-31

Brief Summary

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This is a controlled clinical trials about traditional Chinese medicine named Qufeng Shengshi Fang,which consisted of cicada slough,bombyx batryticatus,radix angelicae,radix sileris,honeysuckle flower,forsythia,lithospermum and radix glycyrrhizae,and Loratadine on treatment of Allergic Rhinitis.There are 180 Patients with allergic rhinitis recruited from Department of Allergy and Traditional Chinese.To carry on statistical analysis of the result of the self and between-group cross-reference by two questionnaires filled before and after treatment.

Detailed Description

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Conditions

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Rhinitis, Allergic, Perennial

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Qufeng Shengshi Fang and Loratadine

Qufeng Shengshi Fang is a traditional Chinese medicine form 8 kinds of herbs. Loratadine is the second generation antihistamines, after converted into its active metabolite Carrie period (carebastine), its antihistamines and allergy effect has been demonstrated in vitro and in vivo tests, also received data from clinical trials.

Group Type EXPERIMENTAL

Qufeng Shengshi Fang and Loratadine

Intervention Type DRUG

The patients with allergic rhinitis are divided into two groups, one is experimental group, and the other is control group.

The experimental group patients are treated with Qufeng by oral, 200ml two times a day and Loratadine by oral,10mg QD

Loratadine

Intervention Type DRUG

The patients with allergic rhinitis are divided into two groups, one is experimental group, and the other is control group.

The control group patients are treated with Loratadine by oral, 10mg QD

Loratadine

Loratadine (INN) is a second-generation H1 histamine antagonist drug used to treat allergies. In structure, it is closely related to tricyclic antidepressants, such as imipramine, and is distantly related to the atypical antipsychotic quetiapine.Loratadine is marketed by Schering-Plough\[needs update\] under several trade names (e.g., Claritin) and also by Shionogi in Japan. It is available as a generic drug and is marketed for its nonsedating properties. In a version named Claritin-D or Clarinase, it is combined with pseudoephedrine, a decongestant; this makes it useful for colds, as well as allergies but adds potential side effects of insomnia, anxiety, and nervousness.

Group Type ACTIVE_COMPARATOR

Qufeng Shengshi Fang and Loratadine

Intervention Type DRUG

The patients with allergic rhinitis are divided into two groups, one is experimental group, and the other is control group.

The experimental group patients are treated with Qufeng by oral, 200ml two times a day and Loratadine by oral,10mg QD

Loratadine

Intervention Type DRUG

The patients with allergic rhinitis are divided into two groups, one is experimental group, and the other is control group.

The control group patients are treated with Loratadine by oral, 10mg QD

Interventions

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Qufeng Shengshi Fang and Loratadine

The patients with allergic rhinitis are divided into two groups, one is experimental group, and the other is control group.

The experimental group patients are treated with Qufeng by oral, 200ml two times a day and Loratadine by oral,10mg QD

Intervention Type DRUG

Loratadine

The patients with allergic rhinitis are divided into two groups, one is experimental group, and the other is control group.

The control group patients are treated with Loratadine by oral, 10mg QD

Intervention Type DRUG

Other Intervention Names

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Claritin,WS1-(X-014)-2004Z

Eligibility Criteria

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Inclusion Criteria

* meet allergic rhinitis (include allergic rhinitis with asthma) diagnostic criteria at Peking Union Medical College Hospital Department of Allergy;
* have allergic rhinitis in episodes.
* without antihistamine,local anaesthetic or traditional Chinese medicine in last months.
* signed the informed consent form.

Exclusion Criteria

* have severe deviation of nasal septum and nasal polyps.
* have nasal surgery or a history of cancer(tumor).
* have other serious illness or evidence of mental disorders.
* female in pregnancy and lactation
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Peking Union Medical College Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Xiaochun Liang, Doctor

Role: STUDY_DIRECTOR

Peking Union Medical College Hospital traditional Chinese medicine department

Locations

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Peking Union Medical College Hospital traditional Chinese medicine department

Beijing, Beijing Municipality, China

Site Status

Countries

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China

Central Contacts

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Xiaoyang Zhang, Doctor

Role: CONTACT

(+86)13910769068

Facility Contacts

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Xiaoyang Zhang, Doctor

Role: primary

(+86)13910769068

Other Identifiers

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JS-958

Identifier Type: -

Identifier Source: org_study_id

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