Palliative Care in Improving Quality of Life in Patients With High Risk Primary or Recurrent Gynecologic Malignancies

NCT ID: NCT02578888

Last Updated: 2019-09-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

95 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-04-30

Study Completion Date

2019-04-30

Brief Summary

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This randomized clinical trial studies a palliative care program in improving the quality of life of patients with high-risk gynecologic malignancies that is original or first tumor in the body (primary) or has come back (recurrent). Palliative care is care given to patients and their families facing the problems associated with life-threatening illness, through the prevention and relief of suffering by means of early identification and impeccable assessment and treatment of pain and other problems, physical, psychosocial and spiritual. Studying a palliative care program may help doctors learn more about patients quality of life, use of healthcare services, and the relief of pain.

Detailed Description

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PRIMARY OBJECTIVES:

I. Validate a model of proactive palliative medicine referral. II. Quantify the impact of palliative care aggressive care at the end-of-life (PCARE) versus PCARE + idiographic assessment on quality of care and patient satisfaction.

III. Utilizing CMO data Investigators will create a cost model for patients randomized to PCARE versus patients refusing randomization.

IV. Determine the impact of a proactive model of palliative care consultation at the time of diagnosis on family/caregivers.

OUTLINE: Patients are randomized 1 of 2 arms.

GROUP I (usual PCARE): Patients complete European Organization for Research and Treatment of Cancer quality of life-30 (EORTCQLQ-30) and Family Satisfaction with Advanced Cancer Care (FAMCARE) questionnaire every 6 weeks for 3 visits.

GROUP II: (usual PCARE + idiographic assessment): Patients complete EORTC QLQ-30, and FAMCARE questionnaire as in Group I and undergo idiographic assessment. Beginning within 4 weeks of their visit with the gynecologic oncologist, patients are referred to outpatient palliative medicine consultation.

After completion of study, patients are followed up periodically .

Conditions

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Cervical Carcinoma Ovarian Carcinoma Primary Peritoneal Carcinoma Recurrent Cervical Carcinoma Recurrent Ovarian Carcinoma Recurrent Uterine Corpus Carcinoma Recurrent Vulvar Carcinoma Uterine Corpus Cancer Vulvar Carcinoma Peritoneal Neoplasms

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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Palliative Therapy

EORTCQLQ-30 and FAMCARE questionnaire every 6 weeks for 3 visits.

Group Type ACTIVE_COMPARATOR

Palliative Therapy

Intervention Type OTHER

Palliative Therapy

Palliative Therapy + idiographic

Intervention Type OTHER

Ancillary studies

Palliative Therapy+ idiographic

EORTC QLQ-30, and FAMCARE questionnaire every 6 weeks for 3 visits plus patients undergo idiographic assessment.

Group Type EXPERIMENTAL

Palliative Therapy

Intervention Type OTHER

Palliative Therapy

Palliative Therapy + idiographic

Intervention Type OTHER

Ancillary studies

Interventions

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Palliative Therapy

Palliative Therapy

Intervention Type OTHER

Palliative Therapy + idiographic

Ancillary studies

Intervention Type OTHER

Other Intervention Names

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Palliative Care Symptom Management Quality of Life Assessment

Eligibility Criteria

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Inclusion Criteria

* Women with of primary or recurrent diagnosis of ovarian, uterine, peritoneal, cervical or vulvar cancer with any of the following:

* \< 30 % projected 5 year survival based on histopathological stage
* Non-pelvic recurrent malignancy
* Persistent or progressive disease despite primary treatment with surgery, chemotherapy or
* Palliative performance scale \< 60
* Enrollment within 6 weeks of tumor board review
Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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National Cancer Institute (NCI)

NIH

Sponsor Role collaborator

Albert Einstein College of Medicine

OTHER

Sponsor Role lead

Responsible Party

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Nicole Nevadunsky

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Nicole Nevadunsky

Role: PRINCIPAL_INVESTIGATOR

Albert Einstein College of Medicine

Locations

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Albert Einstein College of Medicine

The Bronx, New York, United States

Site Status

Countries

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United States

Other Identifiers

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NCI-2015-00729

Identifier Type: REGISTRY

Identifier Source: secondary_id

2014-4421

Identifier Type: OTHER

Identifier Source: secondary_id

P30CA013330

Identifier Type: NIH

Identifier Source: secondary_id

View Link

2014-4421

Identifier Type: -

Identifier Source: org_study_id

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